Dec. 9, 2019 Repairing faulty genes to prevent and cure disease is something researchers have been working towards for many years. While Class 2 CRISPR systems show great promise as gene editing tools in human ...
Sep. 25, 2019 A new therapeutic being tested is showing early promise as a more effective treatment that could help nearly half of patients with Duchenne muscular dystrophy (DMD). The treatment -- a cocktail of ...
Sep. 24, 2019 A new clinical trial found a cost-effective generic drug works just as well as a more expensive drug in preserving heart function in boys with Duchenne muscular ...
July 18, 2019 A team has identified a gene that could make immunotherapy treatments, specifically checkpoint inhibitors, work for a wider variety of cancer patients. The study found that when the DUX4 gene is ...
June 7, 2019 Muscle decline caused by ageing and certain diseases could be dramatically slowed by stopping a chain reaction that damages cells, new research ...
June 3, 2019 Researchers have found that lithium improves muscle size and strength in mice with a rare form of muscular dystrophy that causes weakness in the shoulders and hips. The findings could lead to a drug ...
Mar. 12, 2019 A research team how a type of protein that is embedded in the inner nuclear membrane clears out of the system once it has served its ...
Feb. 27, 2019 By sequencing the entire genomes of tumor cells from six people with a rare cancer of the nose and sinus cavity, researchers report they unexpectedly found the same genetic change -- one in a gene ...
Feb. 21, 2019 Patients with Duchenne muscular dystrophy (DMD) have few treatment options. Medications currently available or in development either target only a subset of DMD patients with a particular genetic ...
Feb. 13, 2019 The University of Minnesota Medical School continues its legacy of advancing cell replacement therapies with a scientific breakthrough that highlights the promise of cell therapies for muscular ...
Feb. 11, 2019 Prednisone, the current standard of care used to treat kids with Duchenne muscular dystrophy (DMD), reduces chronic inflammation but has harsh side effects. Eplerenone, a heart failure drug, is used ...
Feb. 1, 2019 Experimental gene therapy cassettes for Duchenne muscular dystrophy have been modified to deliver better performance. The cassettes, which carry the therapy into muscle cells, contain newer versions ...
Jan. 31, 2019 Researchers have discovered a new way to treat the loss of muscle function caused by Duchenne muscular dystrophy in animal models of the disease. The team restored muscle stem cell function that is ...
Dec. 12, 2018 To help patients with muscle disorders, scientists have engineered a new stem cell line to study the conversion of stem cells into ...
Nov. 19, 2018 Myotubular myopathy is a severe genetic disease that leads to muscle paralysis. Although no treatment currently exists, researchers have identified a molecule that not only greatly reduces the ...
Sep. 20, 2018 A head-to-head trial comparing the decades-old steroid, prednisone, and a promising new steroid, vamorolone, finds both act on the same key set of genetic pathways involved in controlling ...
Sep. 11, 2018 Answers to treating muscular dystrophies could lie in better understanding muscle repair -- which resembles a delicate cellular dance choreographed by special cells called fibro-adipogenic ...
Aug. 27, 2018 People with a form of heart disease called cardiomyopathy have abnormally short telomeres in heart muscle cells responsible for contraction, according to a new ...
Aug. 27, 2018 In a head-to-head trial between the conventional glucocorticoid, prednisolone, and a modified glucocorticoid, vamorolone, in experimental models of LGMD2B, vamorolone improved dysferlin-deficient ...
July 5, 2018 Researchers have developed a process to regenerate skeletal muscle cells in mice with muscular ...
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