Sep. 1, 2020 — In laboratory studies, researchers observed a key step in how cancer cells may spread from a primary tumor to a distant site within the body, a process known as ...
Aug. 28, 2020 — Research has identified a small molecule compound that can activate the Wnt pathway in non-Wnt subtypes of medulloblastoma, making these aggressive forms of cancer more responsive to therapies. The ...
Aug. 27, 2020 — Researchers have discovered how brain cancer cells increase production of a key protein that allows them to evade the body's immune system. The study suggests that targeting this cellular ...
Aug. 19, 2020 — Researchers have discovered that removing copper from the blood can destroy some of the deadliest cancers that are resistant to immunotherapy using models of the ...
July 29, 2020 — More than 200 genes with novel and known roles in glioblastoma - the most aggressive type of brain cancer - offer promising new drug targets. Researchers engineered a new mouse model to show for the ...
July 22, 2020 — A mouse model of glioblastoma, an aggressive type of cancer that can occur in the brain, suggests that this recalcitrant cancer originates from a pool of stem cells that can be a significant distance ...
July 14, 2020 — Therapies for treating glioblastoma brain cancer can be delivered with greater precision and existing drugs can be used in new ways. These are the conclusions from a stud investigating a large number ...
May 1, 2020 — People with the genetic condition neurofibromatosis type 1 (NF1) are prone to developing tumors on nervous system tissue. A new study has found that the development and growth of such tumors are ...
Apr. 27, 2020 — Researchers developed a novel approach that delivers appropriately-targeted chimeric antigen receptor (CAR) T cell therapy directly into the cerebrospinal fluid that surrounds recurrent pediatric ...
Apr. 14, 2020 — The first sign of trouble for a patient with a growing brain tumor is often a seizure. Such seizures have long been considered a side effect of the tumor. But now a joint team of Columbia engineers ...
Apr. 9, 2020 — Researchers created technology that uses optical imaging to better help surgeons map out tumors in the body and help them understand how certain diseases affect activity in the ...
Apr. 6, 2020 — Unprovoked recurrent seizures are a serious problem affecting most patients who suffer from glioma, a primary brain tumor composed of malignant glial cells. Researchers tested the hypothesis that ...
Mar. 31, 2020 — Scientists have identified a novel target for a type of pediatric brain ...
Mar. 25, 2020 — The pediatric brain cancer known as diffuse intrinsic pontine glioma (DIPG) is almost uniformly fatal. In part, this is due to where and how it grows, forming as a diffuse net of cells in a part of ...
Mar. 4, 2020 — Scientists have developed and tested the first chimeric antigen receptor (CAR) T cell therapy using chlorotoxin (CLTX), a component of scorpion venom, to direct T cells to target brain tumor cells, ...
Feb. 27, 2020 — New research shows brain imaging may be able to predict when a blood test known as a liquid biopsy would or would not produce clinically actionable information, allowing doctors to more efficiently ...
Feb. 26, 2020 — The deadly brain cancer glioblastoma (GBM) is often resistant to chemotherapy and radiation, but new research shows targeting stromal cells -- the cells that serve as the connective tissue of the ...
Feb. 17, 2020 — In experiments with human cells and mice, researchers report evidence that combining the experimental cancer medication TAK228 (also called sapanisertib) with an existing anti-cancer drug called ...
Feb. 10, 2020 — For cancers such as glioma, preclinical research models have failed to provide sufficient insight for medical progress. A team has now thoroughly analyzed sporadic canine gliomas and found that their ...
Jan. 29, 2020 — Scientists discovered that glioma, a lethal form of brain cancer, alters the activity of neighboring neurons, accelerating a vicious cycle that drives tumor-associated epilepsy and tumor ...
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