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Top Headlines

Dangerous Bacteria Communicate to Avoid Antibiotics

Nov. 22, 2019 — Researchers have found a new survival mechanism for a commonly known type of bacteria. It can send out warning signals and thus make sure that other bacteria escape 'dangers' such as antibiotics. The ...

Three-Drug Combo Improves Lung Function in Most Common Genetic Form of Cystic Fibrosis

Oct. 31, 2019 — A phase three clinical trial determined that a 3-drug combination improved lung function and reduced symptoms in cystic fibrosis (CF) patients who ...

Potential Cystic Fibrosis Treatment Uses 'Molecular Prosthetic' for Missing Lung Protein

Mar. 13, 2019 — An approved drug normally used to treat fungal infections could also do the job of a protein channel that is missing or dysfunctional in the lungs of ...

New Lung Cell Type Discovered

Aug. 1, 2018 — Two research teams report the discovery of a new, rare type of cell in the human airway. These cells appear to be the primary source of activity of the CFTR gene, mutations to which cause cystic ...

Latest Headlines

updated 10:58pm EDT

Cystic Fibrosis: Why So Many Respiratory Complications?

July 13, 2020 — Cystic fibrosis causes severe respiratory and digestive disorders. Despite considerable therapeutic advances, this disease still reduces life expectancy, in particular due to life-threatening ...

A Newly Discovered Disease May Lead to Better Treatment of Cystic Fibrosis

June 5, 2020 — Cystic fibrosis is the most frequent severe inherited disorder worldwide. Researchers have now discovered a novel disease that might lead to a better understanding of cystic fibrosis and new ...

Plant-Based Relatives of Cholesterol Could Give Boost to Gene Therapy

Feb. 20, 2020 — Gene-infused nanoparticles used for combating disease work better when they include plant-based relatives of cholesterol because their shape and structure help the genes get where they need to be ...

Curing Genetic Disease in Human Cells

Feb. 20, 2020 — Scientists show for the first time that a newer type of CRISPR, called base-editing, can safely cure cystic fibrosis in stem cells derived from ...

New Treatment Kills Off Infection That Can Be Deadly to Cystic Fibrosis Patients

Jan. 27, 2020 — Scientists have combined doses of three antibiotics -- amoxicillin and imipenem-relebactam and found it was 100% effective in killing off the ...

Disease-Causing Protein in Cystic Fibrosis Has Ancient Roots in Sea Lamprey

Oct. 31, 2019 — The oldest known ortholog of the ion channel that is defective in patients with cystic fibrosis arose approximately 450 million years ago in the sea lamprey, researchers report. Many differences ...

In Cystic Fibrosis, Lungs Feed Deadly Bacteria

Aug. 21, 2019 — A steady supply of its favorite food helps a deadly bacterium thrive in the lungs of people with cystic fibrosis, according to a new ...

Hinge-Like Protein May Open New Doors in Cystic Fibrosis Treatment

July 9, 2019 — Drugs known as potentiators alleviate some symptoms of cystic fibrosis. Researchers recently figured out how these compounds work--a finding that may lead to better drugs that patients can more ...

Discovery Shows How Mucus Build-Up, Not Infections, Triggers Cystic Fibrosis Lung Damage

Apr. 3, 2019 — The build-up of abnormally thick mucus and the associated inflammation appear to be the initiating cause of damage to the lungs of children with ...

Determining What Binds to Mucus

Mar. 13, 2019 — The human body is full of mucus. This viscous goo isn't just a nuisance that gets coughed up or sneezed out -- it can bind to drugs, toxins or microbes, potentially impacting human health. However, ...