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Huntington's Disease News
December 19, 2020

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New Method to Map Cholesterol Metabolism in Brain

Researchers have developed new technology to monitor cholesterol in brain tissue which could uncover its relation to neurodegenerative disease and pave the way for the development of new ...

Q-Suite Motor Assessment Tool Promising for Evaluating Huntington's Disease

In clinical trials of adults with Huntington's disease (HD) the Q-Suite Motor Assessment Tool (Q-Motor) has proven to be helpful to detect and quantitate subtle motor abnormalities. With the ...

Insight Into Cells' 'Self-Eating' Process Could Pave the Way for New Dementia Treatments

Cells regularly go through a process called autophagy -- literally translated as 'self-eating' -- which helps to destroy bacteria and viruses after infection. Now new research has shed ...

Searching for the Origins of the Depressive Symptoms in Huntington's Disease

An altered function of Cdk5 kinase -- an essential enzyme in several cell signalling pathways -- could explain the physiopathology of the depressive-like behavior in Huntington's ...

Blood Pressure Drug Shows Promise for Treating Parkinson's and Dementia in Animal Study

A prescribed drug to treat high blood pressure has shown promise against conditions such as Parkinson's, Huntington's and forms of dementia in studies carried out in mice and ...

New Role for Sensory Signals in the Brain

Learning how to tie a shoe or shoot a basketball isn't easy, but the brain somehow integrates sensory signals that are critical to coordinating movements so you can get it right. Now, scientists ...

Abnormalities in a Protein Affecting How Nerve Cells Change Shape

Since 1993, when the gene that causes Huntington's disease (HD) was identified, there has been intense focus on understanding how this genetic mutation causes the disease's severe ...

Circadian Clock Plays Unexpected Role in Neurodegenerative Diseases

Researchers induced jet lag in a fruit fly model of Huntington disease and found that jet lag protected the flies' ...

How Nerve Cells Control Misfolded Proteins

Researchers have identified a protein complex that marks misfolded proteins, stops them from interacting with other proteins in the cell and directs them towards disposal. They have identified the ...

West Virginia Study Details Promising Method for Estimating Rural Intravenous Drug Use

A study estimates that 1,857 people injected drugs in the last six months in Cabell County, W.Va., a rural county with a population of 94,958. This estimate is based on an innovative survey technique ...

Speeding Up Genetic Diagnosis of Huntington's Disease

Elongated segments of DNA cause Huntington's disease and certain other disorders of the brain. Researchers have developed a method to determine the length of the mutated genes quickly and ...

A New Hope in Treating Neurodegenerative Disease

Researchers have clarified the fundamentals of coiled toxin protein which causes neurodegenerative brain disorders. The result is expected to speed the development of treatment for neurodegenerative ...

How Neurons Could Disconnect from Each Other in Huntington's Disease

Newly described mechanism called 'neuritosis' could play an important role in normal brain development, aging and neurodegenerative ...

The Brain's Support Cells Show Defective Development in Huntington's Disease

The neurological disorder Huntington's disease causes behavioral and motor changes, which among other things are a result of dysfunctional maturation or formation of glial cells, the ...

New Study Offers Hope for Patients Suffering from a Rare Form of Blindness

A new form of therapy may halt or even reverse a form of progressive vision loss that, until now, has inevitably led to blindness. This hyper-targeted approach offers hope to individuals living with ...

Blood and Brain Fluid Change First in Huntington's Disease

A simple blood test can detect the earliest changes caused by Huntington's disease, even before scans can pick up any signs in the brain, a new study has ...

Predict the Onset and Course of Huntington's Disease

Short protein fibers precede the formation of larger deposits that accumulate in the brains of those affected by the incurable Huntington's disease, sometimes called Huntington's chorea, ...

Earlier Diagnosis, Potential Therapy for Huntington's Disease Suggested in New Research

A new study suggests that Huntington's disease may take effect much earlier in life than was previously believed, and that a new drug may be key in controlling the ...

Powerful Molecules Provide New Findings About Huntington's Disease

Researchers have discovered a direct link between the protein aggregation in nerve cells that is typical for neurodegenerative diseases, and the regulation of gene expression in Huntington's ...

Researchers Discover System That Could Reduce Neurodegeneration in Huntington's Disease

Neuroscientists have made an important step towards understanding the mechanisms that cause the neurodegenerative disorder Huntington's disease. Particularly, they identified a system blocking ...

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