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Pharmaceuticals News
October 8, 2020

Top Headlines
 

Medicine for Multiple Sclerosis Patients Inhibits Coronavirus -- At Least in a Test Tube

A drug which has already been approved for the treatment of multiple sclerosis patients effectively inhibits the coronavirus when tested on human ...

Repurposed Anti-Malarial Compounds Kill Diarrheal Parasite, Study Finds

A class of compounds used for malaria treatment also kill the intestinal parasite Cryptosporidium, a leading cause of diarrheal disease and death in children that has no cure, a multi-institution ...

Drugs Aren't Typically Tested on Women -- Artificial Intelligence Could Correct That Bias

Researchers have developed a machine learning algorithm that identifies and predicts differences in adverse drug effects between men and women by ...

Customizable Synthetic Antibiotic Outmaneuvers Resistant Bacteria

Antibiotic resistance is one of the world's most urgent public health threats. In the United States alone, tens of thousands of deaths result each year from drug-resistant strains of common bacteria ...
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Genetic Testing Cost Effective for Newly Diagnosed GIST

Researchers reported that genetic testing is cost-effective and beneficial for newly diagnosed patients with metastatic gastrointestinal stromal tumors (GIST), a rare type of ...

Study Provides Additional Support for Use of New Class of Diabetes Drugs

A new study has assessed the cardiovascular and renal outcomes for ertugliflozin, an SGLT2 inhibitor prescribed for patients with type 2 diabetes to help them control blood sugar ...

Opening an Autophagy Window as the Apoptosis Door Starts to Close

Researchers have successfully attached the cancer cell-targeting antibody Trastuzumab to a previously reported supermolecule that induces autophagic cell death. The antibody-drug conjugate (ADC) ...

A Scientific First: How Psychedelics Bind to Key Brain Cell Receptor

For the first time, scientists solved the high-resolution structure of these compounds when they are actively bound to the 5-HT2A serotonin receptor on the surface of brain cells. This discovery is ...

Many Practitioners Are Not Prescribing HIV Prevention Medication

Only about 54% of medical practitioners surveyed say they have prescribed pre-exposure prophylaxis, or PrEP, to HIV-vulnerable patients, according to a new ...

Why the Dose Matters: Study Shows Levels and Anti-Tumor Effectiveness of a Common Drug Vary Widely

When used to manage infections, the drug itraconazole is generally given at a single, fixed dose to all patients. But determining the correct dosage of the drug to help treat cancer isn't that ...

New Smart Drug Delivery System May Help Treatment for Neurological Disorders

A research team has created a smart drug delivery system that reduces inflammation in damaged nervous tissues and may help treat spinal cord injuries and other neurological disorders. The system, ...

Potential COVID-19 Drug Azithromycin May Increase Risk for Cardiac Events

Azithromycin -- a commonly-prescribed antibiotic -- also is being investigated as a potential treatment for COVID-19. Researchers have found that azithromycin by itself is not associated with an ...

Identifying, Preventing and Managing Heart Rhythm Side Effects of Medicines

Arrhythmias are irregular heartbeats and can be caused by a variety of factors, such as genetics, heart disease, high blood pressure or electrolyte imbalances. Many commonly used medications, ...

Combining Two Precision Medicines Can Treat Drug-Resistant Cancers

Launching a dual-pronged attack on tumours using a combination of two innovative precision medicines could treat patients with multiple common cancers, a new clinical trial ...

New Drug Could Stop Deadly Superbug, Save Tens of Thousands of Lives

Researchers have developed small molecules to combat deadly, drug-resistant ...

New Way to Target Some Rapidly Dividing Cancer Cells, Leaving Healthy Cells Unharmed

Scientists say they have found a new way to kill some multiplying human breast cancer cells by selectively attacking the core of their cell division ...

New Nanosystem Enhances Treatment for Melanoma in Animal Models

Researchers have developed an innovative nanotechnological drug delivery system that significantly enhances the effectiveness of treatment for the aggressive skin cancer ...

Targeted Drug Found Effective in Patients Who Have Lung Cancer With Certain Mutations

A targeted therapy called capmatinib can provide significant benefits to patients who have advanced lung cancer with specific gene mutations, according to recently published results from a phase two ...

'One Size Fits All' Medication Approach Doesn't Work in Pregnancy

New research shows that a blanket approach to prescribing medication during pregnancy may put low birth weight babies at risk for the rest of their ...

Genetic Study of Proteins Is a Breakthrough in Drug Development for Complex Diseases

An innovative genetic study of blood protein levels has demonstrated how genetic data can be used to support drug target prioritization by identifying the causal effects of proteins on ...

Gene Test Can Predict Risk of Medications Causing Liver Injury

Scientists have identified a 'polygenic risk score' that shows when a medication poses a risk of liver ...

New Drug Shown to Improve Bone Growth in Children With Achondroplasia

A phase three global clinical trial has shown that the drug vosoritide restores close-to-average bone growth rates of children with achondroplasia, the most common form of dwarfism. The study ...

New Computational Tool Enables Prediction of Key Functional Sites in Proteins Based on Structure

A new technology that uses a protein's structure to predict the inner wiring that controls the protein's function and dynamics is now available for scientists to utilize. The tool may be ...

Tiny Biological Package Gets Drug Right to the 'Heart' of Transplant Rejection

For patients who receive a heart transplant in the near future, the old adage, 'Good things come in small packages,' may become words to live by. Researchers have demonstrated in mice that ...

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