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Antidepressant

An antidepressant is a medication designed to treat or alleviate the symptoms of clinical depression.

Some antidepressants, notably the tricyclics, are commonly used off-label in the treatment of neuropathic pain, whether or not the patient is depressed.

Note: The above text is excerpted from the Wikipedia article "Antidepressant", which has been released under the GNU Free Documentation License.

For more information, see the following related content on ScienceDaily:

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Getting the Right Treatment: Predicting Treatment Response in Depression

Dec. 28, 2017 — New evidence from mice suggests why an antidepressant treatment can alleviate depression in one person but not ...

Aerobic Exercise Has Antidepressant Treatment Effects

Oct. 18, 2018 — An analysis of randomized controlled clinical trials indicates that supervised aerobic exercise has large antidepressant treatment effects for patients with major ...

Algorithm Identifies Patients Best Suited for Antidepressants

July 17, 2018 — Results of a new study bring us closer to identifying individuals likely to benefit from ...

Adult Stem Cell Study Shows Fish Oil May Help With Depression

June 11, 2020 — A new study shows that patient-derived adult stem cells can be used to model major depressive disorder and test how a patient may respond to medication and that fish oil, when tested in the model, ...

Drug Combination for Treatment Resistant Depression No More Effective Than Single

Nov. 1, 2018 — A large clinical trial, looked at the effectiveness of adding mirtazapine to an SSRI or SNRI in patients who remain depressed after at least six weeks of conventional (SSRI or SNRI) antidepressant ...

Promising Advance in Depression Research

Apr. 8, 2020 — Despite their effectiveness, only 40% of patients respond to the first antidepressant they try. A recent article strongly suggests that a particular protein, GPR56, is involved in the biology of ...

Ketamine Activates Opioid System to Treat Depression

Aug. 29, 2018 — A new study finds that ketamine's acute antidepressant effect requires opioid system activation, the first time that a receptor site has been shown in humans to be necessary for any ...

Antipsychotics for Treating Adult Depression Linked With Higher Mortality

Sep. 30, 2020 — Researchers have reported an increased mortality risk in adults with depression who initiated augmentation with newer antipsychotic medications compared to a control group that initiated augmentation ...

Number of Depressed Over-65s Unchanged but Antidepressant Use Soars

Oct. 7, 2019 — The proportion of people aged over 65 on antidepressants has more than doubled in two decades -- according to new research. Despite a rise in antidepressant use, there was little change in the number ...

New Theory May Explain Cause of Depression and Improve Treatments

Aug. 9, 2018 — Researchers suggest dysfunction in mitochondria -- the main source of energy for cells -- may be the root cause of depression. The finding brings new insight to long-held theories of the causes of ...

Science News

October 29, 2020

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Positive Outlook Predicts Less Memory Decline

Oct. 29, 2020 — A new study finds that people who feel enthusiastic and cheerful -- what psychologists call 'positive affect' -- are less likely to experience memory decline as they age. ...

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Touch and Taste? It's All in the Tentacles

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Where Were Jupiter and Saturn Born?

Oct. 29, 2020 — New work reveals the likely original locations of Saturn and Jupiter. These findings refine our understanding of the forces that determined our Solar System's unusual ...

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A Drop in Temperature

Oct. 28, 2020 — In the nearly two centuries since 98.6 degrees Fahrenheit (37.0 degrees Celsius) was established as the standard 'normal' body temperature, it has been used as the measure by ...

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