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Volume 11(2);  2021 Feb

Reviews

Targeting Non-Oncogene Addiction for Cancer Therapy
Hae Ryung Chang, Eunyoung Jung, Soobin Cho, Young-Jun Jeon, Yonghwan Kim
Biomolecules. 2021 Feb; 11(2): 129. Published online 2021 Jan 20. doi: 10.3390/biom11020129
PMCID:
PMC7909239
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Minimal Residual Disease, Metastasis and Immunity
Jordi Badia-Ramentol, Jenniffer Linares, Andrea Gómez-Llonin, Alexandre Calon
Biomolecules. 2021 Feb; 11(2): 130. Published online 2021 Jan 20. doi: 10.3390/biom11020130
PMCID:
PMC7909268
Article PubReader PDF–816KCite
Autophagy: Mechanisms and Therapeutic Potential of Flavonoids in Cancer
Xuening Pang, Xiaoyi Zhang, Yuhuan Jiang, Quanzhong Su, Qun Li, Zichao Li
Biomolecules. 2021 Feb; 11(2): 135. Published online 2021 Jan 21. doi: 10.3390/biom11020135
PMCID:
PMC7911475
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Heparan Sulfate Glycosaminoglycans: (Un)Expected Allies in Cancer Clinical Management
Isabel Faria-Ramos, Juliana Poças, Catarina Marques, João Santos-Antunes, Guilherme Macedo, Celso A. Reis, Ana Magalhães
Biomolecules. 2021 Feb; 11(2): 136. Published online 2021 Jan 21. doi: 10.3390/biom11020136
PMCID:
PMC7911160
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Urm1: A Non-Canonical UBL
Martin Termathe, Sebastian A. Leidel
Biomolecules. 2021 Feb; 11(2): 139. Published online 2021 Jan 22. doi: 10.3390/biom11020139
PMCID:
PMC7911844
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The Mitochondrial Citrate Carrier SLC25A1/CIC and the Fundamental Role of Citrate in Cancer, Inflammation and Beyond
Rami Mosaoa, Anna Kasprzyk-Pawelec, Harvey R. Fernandez, Maria Laura Avantaggiati
Biomolecules. 2021 Feb; 11(2): 141. Published online 2021 Jan 22. doi: 10.3390/biom11020141
PMCID:
PMC7912299
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The Role of H3K4 Trimethylation in CpG Islands Hypermethylation in Cancer
Giuseppe Zardo
Biomolecules. 2021 Feb; 11(2): 143. Published online 2021 Jan 22. doi: 10.3390/biom11020143
PMCID:
PMC7912453
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Structural Insights into Substrate Recognition and Processing by the 20S Proteasome
Indrajit Sahu, Michael H. Glickman
Biomolecules. 2021 Feb; 11(2): 148. Published online 2021 Jan 24. doi: 10.3390/biom11020148
PMCID:
PMC7910952
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Lipoxygenase Inhibition by Plant Extracts
Melita Lončarić, Ivica Strelec, Tihomir Moslavac, Drago Šubarić, Valentina Pavić, Maja Molnar
Biomolecules. 2021 Feb; 11(2): 152. Published online 2021 Jan 25. doi: 10.3390/biom11020152
PMCID:
PMC7911790
Article PubReader PDF–321KCite
Galectin-3 and sST2 as Prognosticators for Heart Failure Requiring Extracorporeal Life Support: Jack n’ Jill
Jianli Bi, Vidu Garg, Andrew R. Yates
Biomolecules. 2021 Feb; 11(2): 166. Published online 2021 Jan 27. doi: 10.3390/biom11020166
PMCID:
PMC7911521
Article PubReader PDF–758KCite
TOR Signaling Pathway in Cardiac Aging and Heart Failure
Nastaran Daneshgar, Peter S. Rabinovitch, Dao-Fu Dai
Biomolecules. 2021 Feb; 11(2): 168. Published online 2021 Jan 27. doi: 10.3390/biom11020168
PMCID:
PMC7911348
Article PubReader PDF–658KCite
ER Stress-Sensor Proteins and ER-Mitochondrial Crosstalk—Signaling Beyond (ER) Stress Response
Vaishali Kumar, Shuvadeep Maity
Biomolecules. 2021 Feb; 11(2): 173. Published online 2021 Jan 28. doi: 10.3390/biom11020173
PMCID:
PMC7911976
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CAPE and Neuroprotection: A Review
Marwa Balaha, Barbara De Filippis, Amelia Cataldi, Viviana di Giacomo
Biomolecules. 2021 Feb; 11(2): 176. Published online 2021 Jan 28. doi: 10.3390/biom11020176
PMCID:
PMC7911454
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Molecular Mechanisms of Epithelial to Mesenchymal Transition Regulated by ERK5 Signaling
Akshita B. Bhatt, Saloni Patel, Margarite D. Matossian, Deniz A. Ucar, Lucio Miele, Matthew E. Burow, Patrick T. Flaherty, Jane E. Cavanaugh
Biomolecules. 2021 Feb; 11(2): 183. Published online 2021 Jan 29. doi: 10.3390/biom11020183
PMCID:
PMC7911413
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The Critical Role of Small RNAs in Regulating Plant Innate Immunity
Saquib Waheed, Muhammad Anwar, Muhammad Asif Saleem, Jinsong Wu, Muhammad Tayyab, Zhangli Hu
Biomolecules. 2021 Feb; 11(2): 184. Published online 2021 Jan 29. doi: 10.3390/biom11020184
PMCID:
PMC7912340
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Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: The Human Herpesviruses Are Back!
Maria Eugenia Ariza
Biomolecules. 2021 Feb; 11(2): 185. Published online 2021 Jan 29. doi: 10.3390/biom11020185
PMCID:
PMC7912523
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Protein Export via the Type III Secretion System of the Bacterial Flagellum
Manuel Halte, Marc Erhardt
Biomolecules. 2021 Feb; 11(2): 186. Published online 2021 Jan 29. doi: 10.3390/biom11020186
PMCID:
PMC7911332
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Human Lectins, Their Carbohydrate Affinities and Where to Find Them
Cláudia D. Raposo, André B. Canelas, M. Teresa Barros
Biomolecules. 2021 Feb; 11(2): 188. Published online 2021 Jan 29. doi: 10.3390/biom11020188
PMCID:
PMC7911577
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Mucopolysaccharidosis Type I: Current Treatments, Limitations, and Prospects for Improvement
Christiane S. Hampe, Jacob Wesley, Troy C. Lund, Paul J. Orchard, Lynda E. Polgreen, Julie B. Eisengart, Linda K. McLoon, Sebahattin Cureoglu, Patricia Schachern, R. Scott McIvor
Biomolecules. 2021 Feb; 11(2): 189. Published online 2021 Jan 29. doi: 10.3390/biom11020189
PMCID:
PMC7911293
Article PubReader PDF–449KCite
Lysosomal Function and Axon Guidance: Is There a Meaningful Liaison?
Rosa Manzoli, Lorenzo Badenetti, Michela Rubin, Enrico Moro
Biomolecules. 2021 Feb; 11(2): 191. Published online 2021 Jan 29. doi: 10.3390/biom11020191
PMCID:
PMC7911486
Article PubReader PDF–637KCite
Aortic Aneurysms, Chronic Kidney Disease and Metalloproteinases
Michele Andreucci, Michele Provenzano, Teresa Faga, Ashour Michael, Gemma Patella, Pasquale Mastroroberto, Giuseppe Filiberto Serraino, Umberto Marcello Bracale, Nicola Ielapi, Raffaele Serra
Biomolecules. 2021 Feb; 11(2): 194. Published online 2021 Jan 30. doi: 10.3390/biom11020194
PMCID:
PMC7912263
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Epigenetics of Alzheimer’s Disease
Matea Nikolac Perkovic, Alja Videtic Paska, Marcela Konjevod, Katarina Kouter, Dubravka Svob Strac, Gordana Nedic Erjavec, Nela Pivac
Biomolecules. 2021 Feb; 11(2): 195. Published online 2021 Jan 30. doi: 10.3390/biom11020195
PMCID:
PMC7911414
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Research Progress on the Cardiac Injury from ACE2 Targeting in SARS-CoV-2 Infection
Hao Sun, Xiaojuan Su, Lingyi Huang, Dezhi Mu, Yi Qu
Biomolecules. 2021 Feb; 11(2): 196. Published online 2021 Jan 30. doi: 10.3390/biom11020196
PMCID:
PMC7911115
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ER Stress and Unfolded Protein Response in Leukemia: Friend, Foe, or Both?
Kelly Féral, Manon Jaud, Céline Philippe, Doriana Di Bella, Stéphane Pyronnet, Kevin Rouault-Pierre, Laurent Mazzolini, Christian Touriol
Biomolecules. 2021 Feb; 11(2): 199. Published online 2021 Jan 30. doi: 10.3390/biom11020199
PMCID:
PMC7911881
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A Changing Paradigm in Heart Transplantation: An Integrative Approach for Invasive and Non-Invasive Allograft Rejection Monitoring
Alessia Giarraputo, Ilaria Barison, Marny Fedrigo, Jacopo Burrello, Chiara Castellani, Francesco Tona, Tomaso Bottio, Gino Gerosa, Lucio Barile, Annalisa Angelini
Biomolecules. 2021 Feb; 11(2): 201. Published online 2021 Feb 1. doi: 10.3390/biom11020201
PMCID:
PMC7912846
Article PubReader PDF–768KCite
Prion Diseases: A Unique Transmissible Agent or a Model for Neurodegenerative Diseases?
Diane L. Ritchie, Marcelo A. Barria
Biomolecules. 2021 Feb; 11(2): 207. Published online 2021 Feb 2. doi: 10.3390/biom11020207
PMCID:
PMC7912988
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The Hulks and the Deadpools of the Cytokinin Universe: A Dual Strategy for Cytokinin Production, Translocation, and Signal Transduction
Tomáš Hluska, Lucia Hlusková, R. J. Neil Emery
Biomolecules. 2021 Feb; 11(2): 209. Published online 2021 Feb 3. doi: 10.3390/biom11020209
PMCID:
PMC7913349
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Molecular and Genetic Mechanisms That Mediate Transmission of Yersinia pestis by Fleas
B. Joseph Hinnebusch, Clayton O. Jarrett, David M. Bland
Biomolecules. 2021 Feb; 11(2): 210. Published online 2021 Feb 3. doi: 10.3390/biom11020210
PMCID:
PMC7913351
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Role of Small GTPase RhoA in DNA Damage Response
Chibin Cheng, Daniel Seen, Chunwen Zheng, Ruijie Zeng, Enmin Li
Biomolecules. 2021 Feb; 11(2): 212. Published online 2021 Feb 3. doi: 10.3390/biom11020212
PMCID:
PMC7913530
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Insulin-Like Growth Factor-1 (IGF-1) and Its Monitoring in Medical Diagnostic and in Sports
Julian Bailes, Mikhail Soloviev
Biomolecules. 2021 Feb; 11(2): 217. Published online 2021 Feb 4. doi: 10.3390/biom11020217
PMCID:
PMC7913862
Article PubReader PDF–1.5MCite
Receptor-Arrestin Interactions: The GPCR Perspective
Mohammad Seyedabadi, Mehdi Gharghabi, Eugenia V. Gurevich, Vsevolod V. Gurevich
Biomolecules. 2021 Feb; 11(2): 218. Published online 2021 Feb 4. doi: 10.3390/biom11020218
PMCID:
PMC7913897
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The Emerging Function of PKCtheta in Cancer
Amandine Nicolle, Ye Zhang, Karine Belguise
Biomolecules. 2021 Feb; 11(2): 221. Published online 2021 Feb 5. doi: 10.3390/biom11020221
PMCID:
PMC7915540
Article PubReader PDF–881KCite
PA28γ: New Insights on an Ancient Proteasome Activator
Paolo Cascio
Biomolecules. 2021 Feb; 11(2): 228. Published online 2021 Feb 5. doi: 10.3390/biom11020228
PMCID:
PMC7915322
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TRPM4 in Cancer—A New Potential Drug Target
Anna Borgström, Christine Peinelt, Paulina Stokłosa
Biomolecules. 2021 Feb; 11(2): 229. Published online 2021 Feb 5. doi: 10.3390/biom11020229
PMCID:
PMC7914809
Article PubReader PDF–808KCite
The Ins and Outs of RAS Effector Complexes
Christina Kiel, David Matallanas, Walter Kolch
Biomolecules. 2021 Feb; 11(2): 236. Published online 2021 Feb 7. doi: 10.3390/biom11020236
PMCID:
PMC7915224
Article PubReader PDF–10MCite
The Application of Nanobody in CAR-T Therapy
Chaolemeng Bao, Quanli Gao, Lin-Lin Li, Lu Han, Bingxiang Zhang, Yijin Ding, Zongpei Song, Ruining Zhang, Jishuai Zhang, Xian-Hui Wu
Biomolecules. 2021 Feb; 11(2): 238. Published online 2021 Feb 8. doi: 10.3390/biom11020238
PMCID:
PMC7914546
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“Cell Membrane Theory of Senescence” and the Role of Bioactive Lipids in Aging, and Aging Associated Diseases and Their Therapeutic Implications
Undurti N. Das
Biomolecules. 2021 Feb; 11(2): 241. Published online 2021 Feb 8. doi: 10.3390/biom11020241
PMCID:
PMC7914625
Article PubReader PDF–6.4MCite
Signaling Nodes Associated with Endoplasmic Reticulum Stress during NAFLD Progression
Ja Hyun Koo, Chang Yeob Han
Biomolecules. 2021 Feb; 11(2): 242. Published online 2021 Feb 8. doi: 10.3390/biom11020242
PMCID:
PMC7915814
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Post-Translational Modifications That Drive Prostate Cancer Progression
Ivana Samaržija
Biomolecules. 2021 Feb; 11(2): 247. Published online 2021 Feb 9. doi: 10.3390/biom11020247
PMCID:
PMC7915076
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Control of Gene Expression by Exosome-Derived Non-Coding RNAs in Cancer Angiogenesis and Lymphangiogenesis
Valeria Arcucci, Steven A. Stacker, Marc G. Achen
Biomolecules. 2021 Feb; 11(2): 249. Published online 2021 Feb 9. doi: 10.3390/biom11020249
PMCID:
PMC7916238
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The Role of Interferons in the Pathogenesis of Sjögren’s Syndrome and Future Therapeutic Perspectives
Nicoletta Del Papa, Antonina Minniti, Maurizio Lorini, Vincenzo Carbonelli, Wanda Maglione, Francesca Pignataro, Nicola Montano, Roberto Caporali, Claudio Vitali
Biomolecules. 2021 Feb; 11(2): 251. Published online 2021 Feb 9. doi: 10.3390/biom11020251
PMCID:
PMC7916411
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Role of Vascular Endothelial Growth Factor (VEGF) in Human Embryo Implantation: Clinical Implications
Xi Guo, Hong Yi, Tin Chiu Li, Yu Wang, Huilin Wang, Xiaoyan Chen
Biomolecules. 2021 Feb; 11(2): 253. Published online 2021 Feb 10. doi: 10.3390/biom11020253
PMCID:
PMC7916576
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Dopamine Receptors and the Kidney: An Overview of Health- and Pharmacological-Targeted Implications
Alejandro Olivares-Hernández, Luis Figuero-Pérez, Juan Jesus Cruz-Hernandez, Rogelio González Sarmiento, Ricardo Usategui-Martin, José Pablo Miramontes-González
Biomolecules. 2021 Feb; 11(2): 254. Published online 2021 Feb 10. doi: 10.3390/biom11020254
PMCID:
PMC7916607
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Highly Specialized Ubiquitin-Like Modifications: Shedding Light into the UFM1 Enigma
Katharina F. Witting, Monique P.C. Mulder
Biomolecules. 2021 Feb; 11(2): 255. Published online 2021 Feb 10. doi: 10.3390/biom11020255
PMCID:
PMC7916544
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A Review on Haematococcus pluvialis Bioprocess Optimization of Green and Red Stage Culture Conditions for the Production of Natural Astaxanthin
Siti Nur Hazwani Oslan, Noor Fazliani Shoparwe, Abdul Hafidz Yusoff, Ainihayati Abdul Rahim, Chang Shen Chang, Joo Shun Tan, Siti Nurbaya Oslan, Kavithraashree Arumugam, Arbakariya Bin Ariff, Ahmad Ziad Sulaiman, Mohd Shamzi Mohamed
Biomolecules. 2021 Feb; 11(2): 256. Published online 2021 Feb 10. doi: 10.3390/biom11020256
PMCID:
PMC7916564
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Cytotoxic Alkaloids Derived from Marine Sponges: A Comprehensive Review
Ahmed M. Elissawy, Ebrahim Soleiman Dehkordi, Negin Mehdinezhad, Mohamed L. Ashour, Pardis Mohammadi Pour
Biomolecules. 2021 Feb; 11(2): 258. Published online 2021 Feb 10. doi: 10.3390/biom11020258
PMCID:
PMC7916819
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Alzheimer’s Disease and Diabetes: Role of Diet, Microbiota and Inflammation in Preclinical Models
Maria Jose Carranza-Naval, Maria Vargas-Soria, Carmen Hierro-Bujalance, Gloria Baena-Nieto, Monica Garcia-Alloza, Carmen Infante-Garcia, Angel del Marco
Biomolecules. 2021 Feb; 11(2): 262. Published online 2021 Feb 10. doi: 10.3390/biom11020262
PMCID:
PMC7916805
Article PubReader PDF–584KCite
Reciprocally-Coupled Gating: Strange Loops in Bioenergetics, Genetics, and Catalysis
Charles W. Carter, Jr., Peter R. Wills
Biomolecules. 2021 Feb; 11(2): 265. Published online 2021 Feb 11. doi: 10.3390/biom11020265
PMCID:
PMC7916928
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Stress Responses in Down Syndrome Neurodegeneration: State of the Art and Therapeutic Molecules
Chiara Lanzillotta, Fabio Di Domenico
Biomolecules. 2021 Feb; 11(2): 266. Published online 2021 Feb 11. doi: 10.3390/biom11020266
PMCID:
PMC7916967
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Nitroaromatic Antibiotics as Nitrogen Oxide Sources
Allison M. Rice, Yueming Long, S. Bruce King
Biomolecules. 2021 Feb; 11(2): 267. Published online 2021 Feb 12. doi: 10.3390/biom11020267
PMCID:
PMC7918234
Article PubReader PDF–5.4MCite
Fabry Disease: Molecular Basis, Pathophysiology, Diagnostics and Potential Therapeutic Directions
Ken Kok, Kimberley C. Zwiers, Rolf G. Boot, Hermen S. Overkleeft, Johannes M. F. G. Aerts, Marta Artola
Biomolecules. 2021 Feb; 11(2): 271. Published online 2021 Feb 12. doi: 10.3390/biom11020271
PMCID:
PMC7918333
Article PubReader PDF–2.6MCite
Novel Regulators of the IGF System in Cancer
Caterina Mancarella, Andrea Morrione, Katia Scotlandi
Biomolecules. 2021 Feb; 11(2): 273. Published online 2021 Feb 12. doi: 10.3390/biom11020273
PMCID:
PMC7918569
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Why Does Hyperuricemia Not Necessarily Induce Gout?
Wei-Zheng Zhang
Biomolecules. 2021 Feb; 11(2): 280. Published online 2021 Feb 14. doi: 10.3390/biom11020280
PMCID:
PMC7918342
Article PubReader PDF–729KCite
Hormonal Regulation of Oligodendrogenesis I: Effects across the Lifespan
Kimberly L. P. Long, Jocelyn M. Breton, Matthew K. Barraza, Olga S. Perloff, Daniela Kaufer
Biomolecules. 2021 Feb; 11(2): 283. Published online 2021 Feb 14. doi: 10.3390/biom11020283
PMCID:
PMC7918364
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The Interrelationships between Intestinal Permeability and Phlegm Syndrome and Therapeutic Potential of Some Medicinal Herbs
Junghyun Park, Tae Joon Choi, Ki Sung Kang, Seo-Hyung Choi
Biomolecules. 2021 Feb; 11(2): 284. Published online 2021 Feb 15. doi: 10.3390/biom11020284
PMCID:
PMC7918952
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Irisin and Incretin Hormones: Similarities, Differences, and Implications in Type 2 Diabetes and Obesity
Nicola Marrano, Giuseppina Biondi, Anna Borrelli, Angelo Cignarelli, Sebastio Perrini, Luigi Laviola, Francesco Giorgino, Annalisa Natalicchio
Biomolecules. 2021 Feb; 11(2): 286. Published online 2021 Feb 15. doi: 10.3390/biom11020286
PMCID:
PMC7918991
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Hormonal Regulation of Oligodendrogenesis II: Implications for Myelin Repair
Jocelyn M. Breton, Kimberly L. P. Long, Matthew K. Barraza, Olga S. Perloff, Daniela Kaufer
Biomolecules. 2021 Feb; 11(2): 290. Published online 2021 Feb 16. doi: 10.3390/biom11020290
PMCID:
PMC7919830
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Pharmacological and Metabolic Significance of Bile Acids in Retinal Diseases
Alice Win, Amanda Delgado, Ravirajsinh N. Jadeja, Pamela M. Martin, Manuela Bartoli, Menaka C. Thounaojam
Biomolecules. 2021 Feb; 11(2): 292. Published online 2021 Feb 16. doi: 10.3390/biom11020292
PMCID:
PMC7920062
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DNA Methylation, Mechanisms of FMR1 Inactivation and Therapeutic Perspectives for Fragile X Syndrome
Veronica Nobile, Cecilia Pucci, Pietro Chiurazzi, Giovanni Neri, Elisabetta Tabolacci
Biomolecules. 2021 Feb; 11(2): 296. Published online 2021 Feb 16. doi: 10.3390/biom11020296
PMCID:
PMC7920310
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Nanobodies Provide Insight into the Molecular Mechanisms of the Complement Cascade and Offer New Therapeutic Strategies
Alessandra Zarantonello, Henrik Pedersen, Nick S. Laursen, Gregers R. Andersen
Biomolecules. 2021 Feb; 11(2): 298. Published online 2021 Feb 17. doi: 10.3390/biom11020298
PMCID:
PMC7922070
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Challenges and Perspective in Integrated Multi-Omics in Gut Microbiota Studies
Eric Banan-Mwine Daliri, Fred Kwame Ofosu, Ramachandran Chelliah, Byong H. Lee, Deog-Hwan Oh
Biomolecules. 2021 Feb; 11(2): 300. Published online 2021 Feb 17. doi: 10.3390/biom11020300
PMCID:
PMC7922017
Article PubReader PDF–828KCite
Small in Size, but Large in Action: microRNAs as Potential Modulators of PTEN in Breast and Lung Cancers
Asal Jalal Abadi, Ali Zarrabi, Mohammad Hossein Gholami, Sepideh Mirzaei, Farid Hashemi, Amirhossein Zabolian, Maliheh Entezari, Kiavash Hushmandi, Milad Ashrafizadeh, Haroon Khan, Alan Prem Kumar
Biomolecules. 2021 Feb; 11(2): 304. Published online 2021 Feb 18. doi: 10.3390/biom11020304
PMCID:
PMC7922700
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Epigenetics and Communication Mechanisms in Microglia Activation with a View on Technological Approaches
Sabrina Petralla, Francesca De Chirico, Andrea Miti, Ottavia Tartagni, Francesca Massenzio, Eleonora Poeta, Marco Virgili, Giampaolo Zuccheri, Barbara Monti
Biomolecules. 2021 Feb; 11(2): 306. Published online 2021 Feb 18. doi: 10.3390/biom11020306
PMCID:
PMC7923060
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Current Views on the Roles of O-Glycosylation in Controlling Notch-Ligand Interactions
Wataru Saiki, Chenyu Ma, Tetsuya Okajima, Hideyuki Takeuchi
Biomolecules. 2021 Feb; 11(2): 309. Published online 2021 Feb 18. doi: 10.3390/biom11020309
PMCID:
PMC7922208
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Organ Fibrosis and Autoimmunity: The Role of Inflammation in TGFβ-Dependent EMT
Margherita Sisto, Domenico Ribatti, Sabrina Lisi
Biomolecules. 2021 Feb; 11(2): 310. Published online 2021 Feb 18. doi: 10.3390/biom11020310
PMCID:
PMC7922523
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Unique Benefits of Tumor-Specific Nanobodies for Fluorescence Guided Surgery
Thinzar M. Lwin, Robert M. Hoffman, Michael Bouvet
Biomolecules. 2021 Feb; 11(2): 311. Published online 2021 Feb 18. doi: 10.3390/biom11020311
PMCID:
PMC7921980
Article PubReader PDF–740KCite
Molecular Targets and Strategies for Inhibition of the Bacterial Type III Secretion System (T3SS); Inhibitors Directly Binding to T3SS Components
Julia A. Hotinger, Heather A. Pendergrass, Aaron E. May
Biomolecules. 2021 Feb; 11(2): 316. Published online 2021 Feb 19. doi: 10.3390/biom11020316
PMCID:
PMC7922566
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Molecular and Biochemical Pathways of Catalpol in Alleviating Diabetes Mellitus and Its Complications
Subrat Kumar Bhattamisra, Hui Min Koh, Shin Yean Lim, Hira Choudhury, Manisha Pandey
Biomolecules. 2021 Feb; 11(2): 323. Published online 2021 Feb 20. doi: 10.3390/biom11020323
PMCID:
PMC7924042
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Zebrafish Tools for Deciphering Habenular Network-Linked Mental Disorders
Anja Bühler, Matthias Carl
Biomolecules. 2021 Feb; 11(2): 324. Published online 2021 Feb 20. doi: 10.3390/biom11020324
PMCID:
PMC7924194
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Actin Cytoskeleton and Regulation of TGFβ Signaling: Exploring Their Links
Roberta Melchionna, Paola Trono, Annalisa Tocci, Paola Nisticò
Biomolecules. 2021 Feb; 11(2): 336. Published online 2021 Feb 23. doi: 10.3390/biom11020336
PMCID:
PMC7926735
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Articles

Impaired Alignment of Bone Matrix Microstructure Associated with Disorganized Osteoblast Arrangement in Malignant Melanoma Metastasis
Aira Matsugaki, Yumi Kimura, Ryota Watanabe, Fumihito Nakamura, Ryo Takehana, Takayoshi Nakano
Biomolecules. 2021 Feb; 11(2): 131. Published online 2021 Jan 20. doi: 10.3390/biom11020131
PMCID:
PMC7909255
Article PubReader PDF–3.1MCite
Innocuous, Highly Conductive, and Affordable Thermal Interface Material with Copper-Based Multi-Dimensional Filler Design
Woochang Kim, Chihyun Kim, Wonseok Lee, Jinsung Park, Duckjong Kim
Biomolecules. 2021 Feb; 11(2): 132. Published online 2021 Jan 20. doi: 10.3390/biom11020132
PMCID:
PMC7909517
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Extra Virgin Olive Oil Phenols Vasodilate Rat Mesenteric Resistance Artery via Phospholipase C (PLC)-Calcium Microdomains-Potassium Channels (BKCa) Signals
Rossana D’Agostino, Laura Barberio, Mariacarmela Gatto, Teresa Tropea, Maria De Luca, Maurizio Mandalà
Biomolecules. 2021 Feb; 11(2): 137. Published online 2021 Jan 21. doi: 10.3390/biom11020137
PMCID:
PMC7912046
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Transgenerational Effects of Hexavalent Chromium on Marine Medaka (Oryzias melastigma) Reveal Complex Transgenerational Adaptation in Offspring
Xiaomin Ni, Yingjia Shen
Biomolecules. 2021 Feb; 11(2): 138. Published online 2021 Jan 22. doi: 10.3390/biom11020138
PMCID:
PMC7911212
Article PubReader PDF–3.3MCite
Isolation and Characterization of Fungal Endophytes Isolated from Medicinal Plant Ephedra pachyclada as Plant Growth-Promoting
Ahmed Mohamed Aly Khalil, Saad El-Din Hassan, Sultan M. Alsharif, Ahmed M. Eid, Emad El-Din Ewais, Ehab Azab, Adil A. Gobouri, Amr Elkelish, Amr Fouda
Biomolecules. 2021 Feb; 11(2): 140. Published online 2021 Jan 22. doi: 10.3390/biom11020140
PMCID:
PMC7911138
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DNA Methylation Profiles of Tph1A and BDNF in Gut and Brain of L. Rhamnosus-Treated Zebrafish
Mariella Cuomo, Luca Borrelli, Rosa Della Monica, Lorena Coretti, Giulia De Riso, Luna D’Angelo Lancellotti di Durazzo, Alessandro Fioretti, Francesca Lembo, Timothy G. Dinan, John F. Cryan, Sergio Cocozza, Lorenzo Chiariotti
Biomolecules. 2021 Feb; 11(2): 142. Published online 2021 Jan 22. doi: 10.3390/biom11020142
PMCID:
PMC7911505
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Clinical Phenotypes of Parkinson’s Disease Associate with Distinct Gut Microbiota and Metabolome Enterotypes
Sarah Vascellari, Marta Melis, Vanessa Palmas, Silvia Pisanu, Alessandra Serra, Daniela Perra, Maria Laura Santoru, Valentina Oppo, Roberto Cusano, Paolo Uva, Luigi Atzori, Micaela Morelli, Giovanni Cossu, Aldo Manzin
Biomolecules. 2021 Feb; 11(2): 144. Published online 2021 Jan 22. doi: 10.3390/biom11020144
PMCID:
PMC7911638
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The Structural Properties of Odorants Modulate Their Association to Human Odorant Binding Protein
Tarsila G. Castro, Carla Silva, Teresa Matamá, Artur Cavaco-Paulo
Biomolecules. 2021 Feb; 11(2): 145. Published online 2021 Jan 22. doi: 10.3390/biom11020145
PMCID:
PMC7912024
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Syntaxin 1A Gene Is Negatively Regulated in a Cell/Tissue Specific Manner by YY1 Transcription Factor, Which Binds to the −183 to −137 Promoter Region Together with Gene Silencing Factors Including Histone Deacetylase
Takahiro Nakayama, Toshiyuki Fukutomi, Yasuo Terao, Kimio Akagawa
Biomolecules. 2021 Feb; 11(2): 146. Published online 2021 Jan 23. doi: 10.3390/biom11020146
PMCID:
PMC7910890
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NTPDase1 Modulates Smooth Muscle Contraction in Mice Bladder by Regulating Nucleotide Receptor Activation Distinctly in Male and Female
Romuald Brice Babou Kammoe, Gilles Kauffenstein, Julie Pelletier, Bernard Robaye, Jean Sévigny
Biomolecules. 2021 Feb; 11(2): 147. Published online 2021 Jan 23. doi: 10.3390/biom11020147
PMCID:
PMC7911947
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Prepubertal Periodontitis in a Patient with Combined Classical and Periodontal Ehlers–Danlos Syndrome
Friedrich Stock, Marcel Hanisch, Sarah Lechner, Saskia Biskup, Axel Bohring, Johannes Zschocke, Ines Kapferer-Seebacher
Biomolecules. 2021 Feb; 11(2): 149. Published online 2021 Jan 24. doi: 10.3390/biom11020149
PMCID:
PMC7912441
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Efficacy of Providing the PI3K p110α Inhibitor BYL719 (Alpelisib) to Middle-Aged Mice in Their Diet
Christopher P. Hedges, Jordi Boix, Jagdish K. Jaiswal, Bhoopika Shetty, Peter R. Shepherd, Troy L. Merry
Biomolecules. 2021 Feb; 11(2): 150. Published online 2021 Jan 25. doi: 10.3390/biom11020150
PMCID:
PMC7911305
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Reconstitution of Human Necrosome Interactions in Saccharomyces cerevisiae
Y. Ji, L. A. Ward, C. J. Hawkins
Biomolecules. 2021 Feb; 11(2): 153. Published online 2021 Jan 25. doi: 10.3390/biom11020153
PMCID:
PMC7911209
Article PubReader PDF–3.7MCite
The Middle Part of the Plucked Hair Follicle Outer Root Sheath Is Identified as an Area Rich in Lineage-Specific Stem Cell Markers
Hanluo Li, Federica Francesca Masieri, Marie Schneider, Alexander Bartella, Sebastian Gaus, Sebastian Hahnel, Rüdiger Zimmerer, Ulrich Sack, Danijela Maksimovic-Ivanic, Sanja Mijatovic, Jan-Christoph Simon, Bernd Lethaus, Vuk Savkovic
Biomolecules. 2021 Feb; 11(2): 154. Published online 2021 Jan 25. doi: 10.3390/biom11020154
PMCID:
PMC7912066
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Type III Collagen is Required for Adipogenesis and Actin Stress Fibre Formation in 3T3-L1 Preadipocytes
Mohammad Al Hasan, Patricia E. Martin, Xinhua Shu, Steven Patterson, Chris Bartholomew
Biomolecules. 2021 Feb; 11(2): 156. Published online 2021 Jan 25. doi: 10.3390/biom11020156
PMCID:
PMC7911635
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MicroRNA-193a-5p Regulates the Synthesis of Polyunsaturated Fatty Acids by Targeting Fatty Acid Desaturase 1 (FADS1) in Bovine Mammary Epithelial Cells
Yongliang Fan, Abdelaziz Adam Idriss Arbab, Huimin Zhang, Yi Yang, Xubin Lu, Ziyin Han, Zhangping Yang
Biomolecules. 2021 Feb; 11(2): 157. Published online 2021 Jan 25. doi: 10.3390/biom11020157
PMCID:
PMC7911131
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4,6,4′-Trimethylangelicin Photoactivated by Blue Light Might Represent an Interesting Option for Photochemotherapy of Non-Invasive Bladder Carcinoma: An In Vitro Study on T24 Cells
Giulio Sturaro, Alessia Tasso, Luca Menilli, Rosa Di Liddo, Giorgia Miolo, Maria Teresa Conconi
Biomolecules. 2021 Feb; 11(2): 158. Published online 2021 Jan 25. doi: 10.3390/biom11020158
PMCID:
PMC7911445
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Transcriptome Analysis Reveals Altered Inflammatory Pathway in an Inducible Glial Cell Model of Myotonic Dystrophy Type 1
Cuauhtli N. Azotla-Vilchis, Daniel Sanchez-Celis, Luis E. Agonizantes-Juárez, Rocío Suárez-Sánchez, J. Manuel Hernández-Hernández, Jorge Peña, Karla Vázquez-Santillán, Norberto Leyva-García, Arturo Ortega, Vilma Maldonado, Claudia Rangel, Jonathan J. Magaña, Bulmaro Cisneros, Oscar Hernández-Hernández
Biomolecules. 2021 Feb; 11(2): 159. Published online 2021 Jan 26. doi: 10.3390/biom11020159
PMCID:
PMC7910866
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Computational Insights into the Potential of Withaferin-A, Withanone and Caffeic Acid Phenethyl Ester for Treatment of Aberrant-EGFR Driven Lung Cancers
Vidhi Malik, Vipul Kumar, Sunil C. Kaul, Renu Wadhwa, Durai Sundar
Biomolecules. 2021 Feb; 11(2): 160. Published online 2021 Jan 26. doi: 10.3390/biom11020160
PMCID:
PMC7911128
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Anti-Inflammatory Effects of Rosmarinic Acid-Loaded Nanovesicles in Acute Colitis through Modulation of NLRP3 Inflammasome
Sonia Marinho, Matilde Illanes, Javier Ávila-Román, Virginia Motilva, Elena Talero
Biomolecules. 2021 Feb; 11(2): 162. Published online 2021 Jan 26. doi: 10.3390/biom11020162
PMCID:
PMC7912577
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Effect of Humanizing Mutations on the Stability of the Llama Single-Domain Variable Region
Miguel A. Soler, Barbara Medagli, Jiewen Wang, Sandra Oloketuyi, Gregor Bajc, He Huang, Sara Fortuna, Ario de Marco
Biomolecules. 2021 Feb; 11(2): 163. Published online 2021 Jan 26. doi: 10.3390/biom11020163
PMCID:
PMC7911018
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LPS Tolerance Inhibits Cellular Respiration and Induces Global Changes in the Macrophage Secretome
Joseph Gillen, Thunnicha Ondee, Devikala Gurusamy, Jiraphorn Issara-Amphorn, Nathan P. Manes, Sung Hwan Yoon, Asada Leelahavanichkul, Aleksandra Nita-Lazar
Biomolecules. 2021 Feb; 11(2): 164. Published online 2021 Jan 27. doi: 10.3390/biom11020164
PMCID:
PMC7918892
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Thymoquinone Protects Neurons in the Cerebellum of Rats through Mitigating Oxidative Stress and Inflammation Following High-Fat Diet Supplementation
Aziza Alrafiah
Biomolecules. 2021 Feb; 11(2): 165. Published online 2021 Jan 27. doi: 10.3390/biom11020165
PMCID:
PMC7911218
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Nanobody-Based Indirect Competitive ELISA for Sensitive Detection of 19-Nortestosterone in Animal Urine
Yuan-yuan Yang, Yu Wang, Yi-feng Zhang, Feng Wang, Yi-fan Liang, Jin-yi Yang, Zhen-lin Xu, Yu-dong Shen, Hong Wang
Biomolecules. 2021 Feb; 11(2): 167. Published online 2021 Jan 27. doi: 10.3390/biom11020167
PMCID:
PMC7912623
Article PubReader PDF–6.8MCite
Molecular Modeling Studies on the Multistep Reactivation Process of Organophosphate-Inhibited Acetylcholinesterase and Butyrylcholinesterase
Jakub Jończyk, Jędrzej Kukułowicz, Kamil Łątka, Barbara Malawska, Young-Sik Jung, Kamil Musilek, Marek Bajda
Biomolecules. 2021 Feb; 11(2): 169. Published online 2021 Jan 27. doi: 10.3390/biom11020169
PMCID:
PMC7912477
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Protective Effect of γ-mangostin Isolated from the Peel of Garcinia mangostana against Glutamate-Induced Cytotoxicity in HT22 Hippocampal Neuronal Cells
Ji Yun Baek, Kiwon Jung, Young-Mi Kim, Hyun-Young Kim, Ki Sung Kang, Young-Won Chin
Biomolecules. 2021 Feb; 11(2): 170. Published online 2021 Jan 27. doi: 10.3390/biom11020170
PMCID:
PMC7910862
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The Effect of Acute Intense Exercise on Activity of Antioxidant Enzymes in Smokers and Non-Smokers
Hadi Nobari, Hamzeh Abdi Nejad, Mehdi Kargarfard, Soghra Mohseni, Katsuhiko Suzuki, José Carmelo Adsuar, Jorge Pérez-Gómez
Biomolecules. 2021 Feb; 11(2): 171. Published online 2021 Jan 27. doi: 10.3390/biom11020171
PMCID:
PMC7910903
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Human Saliva-Mediated Hydrolysis of Eugenyl-β-D-Glucoside and Fluorescein-di-β-D-Glucoside in In Vivo and In Vitro Models
Mariusz Dziadas, Adam Junka, Henryk Jeleń
Biomolecules. 2021 Feb; 11(2): 172. Published online 2021 Jan 27. doi: 10.3390/biom11020172
PMCID:
PMC7911702
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Ethylene-Cytokinin Interaction Determines Early Defense Response of Wheat against Stagonospora nodorum Berk.
Svetlana V. Veselova, Tatyana V. Nuzhnaya, Guzel F. Burkhanova, Sergey D. Rumyantsev, Elza K. Khusnutdinova, Igor V. Maksimov
Biomolecules. 2021 Feb; 11(2): 174. Published online 2021 Jan 28. doi: 10.3390/biom11020174
PMCID:
PMC7911247
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The α6 GABAA Receptor Positive Allosteric Modulator DK-I-56-1 Reduces Tic-Related Behaviors in Mouse Models of Tourette Syndrome
Roberto Cadeddu, Daniel E. Knutson, Laura J. Mosher, Stefanos Loizou, Karen Odeh, Janet L. Fisher, James M. Cook, Marco Bortolato
Biomolecules. 2021 Feb; 11(2): 175. Published online 2021 Jan 28. doi: 10.3390/biom11020175
PMCID:
PMC7912006
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Single-Cell Gene Network Analysis and Transcriptional Landscape of MYCN-Amplified Neuroblastoma Cell Lines
Daniele Mercatelli, Nicola Balboni, Alessandro Palma, Emanuela Aleo, Pietro Paolo Sanna, Giovanni Perini, Federico Manuel Giorgi
Biomolecules. 2021 Feb; 11(2): 177. Published online 2021 Jan 28. doi: 10.3390/biom11020177
PMCID:
PMC7912277
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Functional and Rheological Properties of Vicia faba L. Protein Isolates
Daniel Żmudziński, Urszula Goik, Paweł Ptaszek
Biomolecules. 2021 Feb; 11(2): 178. Published online 2021 Jan 28. doi: 10.3390/biom11020178
PMCID:
PMC7911567
Article PubReader PDF–711KCite
Effect of Postnatal Nutritional Environment Due to Maternal Diabetes on Beta Cell Mass Programming and Glucose Intolerance Risk in Male and Female Offspring
Danièle Bailbe, Junjun Liu, Pengfei Gong, Bernard Portha
Biomolecules. 2021 Feb; 11(2): 179. Published online 2021 Jan 28. doi: 10.3390/biom11020179
PMCID:
PMC7911592
Article PubReader PDF–1.3MCite
BanLec-eGFP Chimera as a Tool for Evaluation of Lectin Binding to High-Mannose Glycans on Microorganisms
Zorana Lopandić, Luka Dragačević, Dragan Popović, Uros Andjelković, Rajna Minić, Marija Gavrović-Jankulović
Biomolecules. 2021 Feb; 11(2): 180. Published online 2021 Jan 28. doi: 10.3390/biom11020180
PMCID:
PMC7912117
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Mining Grapevine Downy Mildew Susceptibility Genes: A Resource for Genomics-Based Breeding and Tailored Gene Editing
Carlotta Pirrello, Tieme Zeilmaker, Luca Bianco, Lisa Giacomelli, Claudio Moser, Silvia Vezzulli
Biomolecules. 2021 Feb; 11(2): 181. Published online 2021 Jan 28. doi: 10.3390/biom11020181
PMCID:
PMC7912118
Article PubReader PDF–8.7MCite
Optimization of Lutein Recovery from Tetraselmis suecica by Response Surface Methodology
Kang Hyun Lee, Ye Won Jang, Hansol Kim, Jang-Seu Ki, Hah Young Yoo
Biomolecules. 2021 Feb; 11(2): 182. Published online 2021 Jan 28. doi: 10.3390/biom11020182
PMCID:
PMC7911107
Article PubReader PDF–6.5MCite
Kaempferitrin-Treated HepG2 Differentially Expressed Exosomal Markers and Affect Extracellular Vesicle Sizes in the Secretome
Wei-Chi Ku, Badrinathan Sridharan, Jiann-Yeu Chen, Jen-Ying Li, Shu-Yu Yang, Meng-Jen Lee
Biomolecules. 2021 Feb; 11(2): 187. Published online 2021 Jan 29. doi: 10.3390/biom11020187
PMCID:
PMC7911751
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Phytogenic Synthesis of Pd-Ag/rGO Nanostructures Using Stevia Leaf Extract for Photocatalytic H2 Production and Antibacterial Studies
Koduru Mallikarjuna, Omaima Nasif, Sulaiman Ali Alharbi, Suresh V. Chinni, Lebaka Veeranjaneya Reddy, Minnam Reddy Vasudeva Reddy, Subramaniam Sreeramanan
Biomolecules. 2021 Feb; 11(2): 190. Published online 2021 Jan 29. doi: 10.3390/biom11020190
PMCID:
PMC7911859
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Hair Histology and Glycosaminoglycans Distribution Probed by Infrared Spectral Imaging: Focus on Heparan Sulfate Proteoglycan and Glypican-1 during Hair Growth Cycle
Charlie Colin-Pierre, Valérie Untereiner, Ganesh D. Sockalingum, Nicolas Berthélémy, Louis Danoux, Vincent Bardey, Solène Mine, Christine Jeanmaire, Laurent Ramont, Stéphane Brézillon
Biomolecules. 2021 Feb; 11(2): 192. Published online 2021 Jan 30. doi: 10.3390/biom11020192
PMCID:
PMC7912031
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Triaging of Culture Conditions for Enhanced Secondary Metabolite Diversity from Different Bacteria
Jenny Schwarz, Georg Hubmann, Katrin Rosenthal, Stephan Lütz
Biomolecules. 2021 Feb; 11(2): 193. Published online 2021 Jan 30. doi: 10.3390/biom11020193
PMCID:
PMC7911347
Article PubReader PDF–3.1MCite
Microwave-Assisted Rapid Green Synthesis of Gold Nanoparticles Using Seed Extract of Trachyspermum ammi: ROS Mediated Biofilm Inhibition and Anticancer Activity
Kahkashan Perveen, Fohad Mabood Husain, Faizan Abul Qais, Altaf Khan, Suhail Razak, Tayyaba Afsar, Pravej Alam, Ali M. Almajwal, Mahmoud M. A. Abulmeaty
Biomolecules. 2021 Feb; 11(2): 197. Published online 2021 Jan 30. doi: 10.3390/biom11020197
PMCID:
PMC7911733
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Different Aggregation Pathways and Structures for Aβ40 and Aβ42 Peptides
Li Wang, Kilho Eom, Taeyun Kwon
Biomolecules. 2021 Feb; 11(2): 198. Published online 2021 Jan 30. doi: 10.3390/biom11020198
PMCID:
PMC7912290
Article PubReader PDF–4.2MCite
Surface Modification of Basalt Fibres with ZnO Nanorods and Its Effect on Thermal and Mechanical Properties of PLA-Based Composites
Francesca Sbardella, Andrea Martinelli, Valerio Di Lisio, Irene Bavasso, Pietro Russo, Jacopo Tirillò, Fabrizio Sarasini
Biomolecules. 2021 Feb; 11(2): 200. Published online 2021 Feb 1. doi: 10.3390/biom11020200
PMCID:
PMC7912728
Article PubReader PDF–5.6MCite
Unravelling the Role of LncRNA WT1-AS/miR-206/NAMPT Axis as Prognostic Biomarkers in Lung Adenocarcinoma
Wen Li, Yu Liu, Zi Jin Li, Yi Shi, Jing Deng, Jie Bai, Liang Ma, Xiao Xi Zeng, Shan Shan Feng, Jia Li Ren, Fei Jun Luo, Duo Yan Rong, Xiao Qi Chen, Hua Qun Yin, Zhu Chen, Fu Da
Biomolecules. 2021 Feb; 11(2): 203. Published online 2021 Feb 2. doi: 10.3390/biom11020203
PMCID:
PMC7912827
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Neuroimmune Response Mediated by Cytokines in Natural Scrapie after Chronic Dexamethasone Treatment
Isabel M. Guijarro, Moisés Garcés, Pol Andrés-Benito, Belén Marín, Alicia Otero, Tomás Barrio, Margarita Carmona, Isidro Ferrer, Juan J. Badiola, Marta Monzón
Biomolecules. 2021 Feb; 11(2): 204. Published online 2021 Feb 2. doi: 10.3390/biom11020204
PMCID:
PMC7912810
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Deoxycholic Acid Upregulates Serum Golgi Protein 73 through Activating NF-κB Pathway and Destroying Golgi Structure in Liver Disease
Danli Yang, Mingjie Yao, Ying Yan, Yanna Liu, Xiajie Wen, Xiangmei Chen, Fengmin Lu
Biomolecules. 2021 Feb; 11(2): 205. Published online 2021 Feb 2. doi: 10.3390/biom11020205
PMCID:
PMC7913056
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Green Synthesis, Characterization, Enzyme Inhibition, Antimicrobial Potential, and Cytotoxic Activity of Plant Mediated Silver Nanoparticle Using Ricinus communis Leaf and Root Extracts
Anadil Gul, Fozia, Asmat Shaheen, Ijaz Ahmad, Baharullah Khattak, Munir Ahmad, Riaz Ullah, Ahmed Bari, Syed Saeed Ali, Abdulrahman Alobaid, Majid M. Asmari, Hafiz M. Mahmood
Biomolecules. 2021 Feb; 11(2): 206. Published online 2021 Feb 2. doi: 10.3390/biom11020206
PMCID:
PMC7913007
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The Quality of Emulsions with New Synthetized Lipids Stabilized by Xanthan Gum
Małgorzata Kowalska, Paweł Turek, Anna Żbikowska, Monika Babut, Jerzy Szakiel
Biomolecules. 2021 Feb; 11(2): 213. Published online 2021 Feb 3. doi: 10.3390/biom11020213
PMCID:
PMC7913472
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Enhanced Production of Photosynthetic Pigments and Various Metabolites and Lipids in the Cyanobacteria Synechocystis sp. PCC 7338 Culture in the Presence of Exogenous Glucose
YuJin Noh, Hwanhui Lee, Myeongsun Kim, Seong-Joo Hong, Hookeun Lee, Dong-Myung Kim, Byung-Kwan Cho, Choul-Gyun Lee, Hyung-Kyoon Choi
Biomolecules. 2021 Feb; 11(2): 214. Published online 2021 Feb 3. doi: 10.3390/biom11020214
PMCID:
PMC7913732
Article PubReader PDF–7.7MCite
Human Eye Optics within a Non-Euclidian Geometrical Approach and Some Implications in Vision Prosthetics Design
Liviu Bilteanu, Ovidiu I. Geicu, Loredana Stanca, Aurelia M. Pisoschi, Florea Serban, Andreea I. Serban, Valentin Calu
Biomolecules. 2021 Feb; 11(2): 215. Published online 2021 Feb 4. doi: 10.3390/biom11020215
PMCID:
PMC7913825
Article PubReader PDF–4.1MCite
Deeper Insights on Alchornea cordifolia (Schumach. & Thonn.) Müll.Arg Extracts: Chemical Profiles, Biological Abilities, Network Analysis and Molecular Docking
Kouadio Ibrahime Sinan, Gunes Ak, Ouattara Katinan Etienne, József Jekő, Zoltán Cziáky, Katalin Gupcsó, Maria João Rodrigues, Luisa Custodio, Mohamad Fawzi Mahomoodally, Jugreet B. Sharmeen, Luigi Brunetti, Sheila Leone, Lucia Recinella, Annalisa Chiavaroli, Giustino Orlando, Luigi Menghini, Massimo Tacchini, Claudio Ferrante, Gokhan Zengin
Biomolecules. 2021 Feb; 11(2): 219. Published online 2021 Feb 4. doi: 10.3390/biom11020219
PMCID:
PMC7913913
Article PubReader PDF–1.9MCite
Diethylstilbestrol Modifies the Structure of Model Membranes and Is Localized Close to the First Carbons of the Fatty Acyl Chains
Alessio Ausili, Inés Rodríguez-González, Alejandro Torrecillas, José A. Teruel, Juan C. Gómez-Fernández
Biomolecules. 2021 Feb; 11(2): 220. Published online 2021 Feb 4. doi: 10.3390/biom11020220
PMCID:
PMC7914449
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The Role of Cardiolipin as a Scaffold Mitochondrial Phospholipid in Autophagosome Formation: In Vitro Evidence
Valeria Manganelli, Antonella Capozzi, Serena Recalchi, Gloria Riitano, Vincenzo Mattei, Agostina Longo, Roberta Misasi, Tina Garofalo, Maurizio Sorice
Biomolecules. 2021 Feb; 11(2): 222. Published online 2021 Feb 5. doi: 10.3390/biom11020222
PMCID:
PMC7915802
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Spermine and Spermidine Priming against Botrytis cinerea Modulates ROS Dynamics and Metabolism in Arabidopsis
Henry Christopher Janse van Rensburg, Anis M. Limami, Wim Van den Ende
Biomolecules. 2021 Feb; 11(2): 223. Published online 2021 Feb 5. doi: 10.3390/biom11020223
PMCID:
PMC7914871
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Nettle-Leaf Extract Derived ZnO/CuO Nanoparticle-Biopolymer-Based Antioxidant and Antimicrobial Nanocomposite Packaging Films and Their Impact on Extending the Post-Harvest Shelf Life of Guava Fruit
Anu Kalia, Manpreet Kaur, Ashwag Shami, Sukhjit Kaur Jawandha, Mousa A. Alghuthaymi, Anirudh Thakur, Kamel A. Abd-Elsalam
Biomolecules. 2021 Feb; 11(2): 224. Published online 2021 Feb 5. doi: 10.3390/biom11020224
PMCID:
PMC7916056
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Ultrasound-Assisted Extraction of Carotenoids from Orange Peel Using Olive Oil and Its Encapsulation in Ca-Alginate Beads
Ivana M. Savic Gajic, Ivan M. Savic, Dragoljub G. Gajic, Aleksandar Dosic
Biomolecules. 2021 Feb; 11(2): 225. Published online 2021 Feb 5. doi: 10.3390/biom11020225
PMCID:
PMC7915125
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Involvement of miR-30a-5p and miR-30d in Endothelial to Mesenchymal Transition and Early Osteogenic Commitment under Inflammatory Stress in HUVEC
Carmen Ciavarella, Ilenia Motta, Francesco Vasuri, Silvia Fittipaldi, Sabrina Valente, Daniela Pollutri, Francesca Ricci, Mauro Gargiulo, Gianandrea Pasquinelli
Biomolecules. 2021 Feb; 11(2): 226. Published online 2021 Feb 5. doi: 10.3390/biom11020226
PMCID:
PMC7915105
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Study of the Cluster Thinning Grape as a Source of Phenolic Compounds and Evaluation of Its Antioxidant Potential
Yolanda Carmona-Jiménez, Miguel Palma, Dominico A. Guillén-Sánchez, M. Valme García-Moreno
Biomolecules. 2021 Feb; 11(2): 227. Published online 2021 Feb 5. doi: 10.3390/biom11020227
PMCID:
PMC7914544
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Repeated Measurements of Cardiac Troponin T and N-Terminal Pro-B-Type Natriuretic Peptide to Assess Long-Term Mortality Risk in Subjects with Osteoarthritis
Martin Rehm, Gisela Büchele, Rolf Erwin Brenner, Klaus-Peter Günther, Hermann Brenner, Wolfgang Koenig, Dietrich Rothenbacher
Biomolecules. 2021 Feb; 11(2): 230. Published online 2021 Feb 5. doi: 10.3390/biom11020230
PMCID:
PMC7915763
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Temperature and Concentration Dependence of Human Whole Blood and Protein Drying Droplets
Anusuya Pal, Amalesh Gope, Germano Iannacchione
Biomolecules. 2021 Feb; 11(2): 231. Published online 2021 Feb 5. doi: 10.3390/biom11020231
PMCID:
PMC7915023
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In Vitro and In Vivo Evaluation of 99mTc-Polymyxin B for Specific Targeting of Gram-Bacteria
Sveva Auletta, Filippo Galli, Michela Varani, Giuseppe Campagna, Martina Conserva, Daniela Martinelli, Iolanda Santino, Alberto Signore
Biomolecules. 2021 Feb; 11(2): 232. Published online 2021 Feb 5. doi: 10.3390/biom11020232
PMCID:
PMC7915610
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Secondary Metabolites, Ferulic Acid and p-Hydroxybenzoic Acid Induced Toxic Effects on Photosynthetic Process in Rumex acetosa L.
M. Iftikhar Hussain, Manuel J. Reigosa
Biomolecules. 2021 Feb; 11(2): 233. Published online 2021 Feb 5. doi: 10.3390/biom11020233
PMCID:
PMC7915730
Article PubReader PDF–1.9MCite
Increased Interleukin-11 and Stress-Related Gene Expression in Human Endothelial and Bronchial Epithelial Cells Exposed to Silver Nanoparticles
Jiyoung Jang, Sun Park, In-Hong Choi
Biomolecules. 2021 Feb; 11(2): 234. Published online 2021 Feb 7. doi: 10.3390/biom11020234
PMCID:
PMC7915395
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Tissue-Specific Landscape of Metabolic Dysregulation during Ageing
Fangrong Zhang, Jakob Kerbl-Knapp, Alena Akhmetshina, Melanie Korbelius, Katharina Barbara Kuentzel, Nemanja Vujić, Gerd Hörl, Margret Paar, Dagmar Kratky, Ernst Steyrer, Tobias Madl
Biomolecules. 2021 Feb; 11(2): 235. Published online 2021 Feb 7. doi: 10.3390/biom11020235
PMCID:
PMC7914945
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Bone Health in Aging Men: Does Zinc and Cuprum Level Matter?
Aleksandra Rył, Tomasz Miazgowski, Aleksandra Szylińska, Agnieszka Turoń-Skrzypińska, Alina Jurewicz, Andrzej Bohatyrewicz, Iwona Rotter
Biomolecules. 2021 Feb; 11(2): 237. Published online 2021 Feb 8. doi: 10.3390/biom11020237
PMCID:
PMC7915903
Article PubReader PDF–543KCite
Xylan Decomposition in Plant Cell Walls as an Inducer of Surfactin Synthesis by Bacillus subtilis
Ida Szmigiel, Dorota Kwiatkowska, Marcin Łukaszewicz, Anna Krasowska
Biomolecules. 2021 Feb; 11(2): 239. Published online 2021 Feb 8. doi: 10.3390/biom11020239
PMCID:
PMC7915361
Article PubReader PDF–2.8MCite
Arabidopsis Defense against the Pathogenic Fungus Drechslera gigantea Is Dependent on the Integrity of the Unfolded Protein Response
Simone Samperna, Angela Boari, Maurizio Vurro, Anna Maria Salzano, Pierluigi Reveglia, Antonio Evidente, Angelo Gismondi, Antonella Canini, Andrea Scaloni, Mauro Marra
Biomolecules. 2021 Feb; 11(2): 240. Published online 2021 Feb 8. doi: 10.3390/biom11020240
PMCID:
PMC7915340
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Oligosaccharides Derived from Tramesan: Their Structure and Activity on Mycotoxin Inhibition in Aspergillus flavus and Aspergillus carbonarius
Jelena Loncar, Barbara Bellich, Alessia Parroni, Massimo Reverberi, Roberto Rizzo, Slaven Zjalić, Paola Cescutti
Biomolecules. 2021 Feb; 11(2): 243. Published online 2021 Feb 8. doi: 10.3390/biom11020243
PMCID:
PMC7914814
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Crucial Role of Juvenile Hormone Receptor Components Methoprene-Tolerant and Taiman in Sexual Maturation of Adult Male Desert Locusts
Michiel Holtof, Joachim Van Lommel, Marijke Gijbels, Elfie Dekempeneer, Bart Nicolai, Jozef Vanden Broeck, Elisabeth Marchal
Biomolecules. 2021 Feb; 11(2): 244. Published online 2021 Feb 9. doi: 10.3390/biom11020244
PMCID:
PMC7915749
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Effect of Rubus idaeus Extracts in Murine Chondrocytes and Explants
Morgane Bourmaud, Mylene Zarka, Romain Le Cozannet, Pascale Fança-Berthon, Eric Hay, Martine Cohen-Solal
Biomolecules. 2021 Feb; 11(2): 245. Published online 2021 Feb 9. doi: 10.3390/biom11020245
PMCID:
PMC7915036
Article PubReader PDF–2.4MCite
Initial Identification of UDP-Glucose Dehydrogenase as a Prognostic Marker in Breast Cancer Patients, Which Facilitates Epirubicin Resistance and Regulates Hyaluronan Synthesis in MDA-MB-231 Cells
Daiana L. Vitale, Ilaria Caon, Arianna Parnigoni, Ina Sevic, Fiorella M. Spinelli, Antonella Icardi, Alberto Passi, Davide Vigetti, Laura Alaniz
Biomolecules. 2021 Feb; 11(2): 246. Published online 2021 Feb 9. doi: 10.3390/biom11020246
PMCID:
PMC7914570
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Profiles of Secondary Metabolites (Phenolic Acids, Carotenoids, Anthocyanins, and Galantamine) and Primary Metabolites (Carbohydrates, Amino Acids, and Organic Acids) during Flower Development in Lycoris radiata
Chang Ha Park, Hyeon Ji Yeo, Ye Jin Kim, Bao Van Nguyen, Ye Eun Park, Ramaraj Sathasivam, Jae Kwang Kim, Sang Un Park
Biomolecules. 2021 Feb; 11(2): 248. Published online 2021 Feb 9. doi: 10.3390/biom11020248
PMCID:
PMC7914633
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Development of Standardized Fetal Progenitor Cell Therapy for Cartilage Regenerative Medicine: Industrial Transposition and Preliminary Safety in Xenogeneic Transplantation
Alexis Laurent, Philippe Abdel-Sayed, Aurélie Ducrot, Nathalie Hirt-Burri, Corinne Scaletta, Sandra Jaccoud, Katja Nuss, Anthony S. de Buys Roessingh, Wassim Raffoul, Dominique Pioletti, Brigitte von Rechenberg, Lee Ann Applegate, Salim Darwiche
Biomolecules. 2021 Feb; 11(2): 250. Published online 2021 Feb 9. doi: 10.3390/biom11020250
PMCID:
PMC7916236
Article PubReader PDF–39MCite
Low-Molecular Weight BDNF Mimetic, Dimeric Dipeptide GSB-106, Reverses Depressive Symptoms in Mouse Chronic Social Defeat Stress
Tatiana A. Gudasheva, Anna V. Tallerova, Armen G. Mezhlumyan, Tatyana A. Antipova, Ilya O. Logvinov, Yulia N. Firsova, Polina Y. Povarnina, Sergey B. Seredenin
Biomolecules. 2021 Feb; 11(2): 252. Published online 2021 Feb 10. doi: 10.3390/biom11020252
PMCID:
PMC7916338
Article PubReader PDF–1.3MCite
Lipoprotein(a) and Cardiovascular Outcomes after Revascularization of Carotid and Lower Limbs Arteries
Marat V. Ezhov, Narek A. Tmoyan, Olga I. Afanasieva, Marina I. Afanasieva, Sergei N. Pokrovsky
Biomolecules. 2021 Feb; 11(2): 257. Published online 2021 Feb 10. doi: 10.3390/biom11020257
PMCID:
PMC7916698
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Green Synthesis of Silver Nanoparticles by Cytobacillus firmus Isolated from the Stem Bark of Terminalia arjuna and Their Antimicrobial Activity
Sujesh Sudarsan, Madan Kumar Shankar, Anil Kumar Belagal Motatis, Sushmitha Shankar, Darshan Krishnappa, Chakrabhavi Dhananjaya Mohan, Kanchugarakoppal S. Rangappa, Vijai Kumar Gupta, Chandra Nayaka Siddaiah
Biomolecules. 2021 Feb; 11(2): 259. Published online 2021 Feb 10. doi: 10.3390/biom11020259
PMCID:
PMC7916701
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Unaltered Liver Regeneration in Post-Cholestatic Rats Treated with the FXR Agonist Obeticholic Acid
Lianne R. de Haan, Joanne Verheij, Rowan F. van Golen, Verena Horneffer-van der Sluis, Matthew R. Lewis, Ulrich H. W. Beuers, Thomas M. van Gulik, Steven W. M. Olde Damink, Frank G. Schaap, Michal Heger, Pim B. Olthof
Biomolecules. 2021 Feb; 11(2): 260. Published online 2021 Feb 10. doi: 10.3390/biom11020260
PMCID:
PMC7916678
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Demystifying Chronic Kidney Disease of Unknown Etiology (CKDu): Computational Interaction Analysis of Pesticides and Metabolites with Vital Renal Enzymes
Harindu Rajapaksha, Dinesh R. Pandithavidana, Jayangika N. Dahanayake
Biomolecules. 2021 Feb; 11(2): 261. Published online 2021 Feb 10. doi: 10.3390/biom11020261
PMCID:
PMC7916818
Article PubReader PDF–40MCite
177Lu-PSMA-617 Therapy in Mice, with or without the Antioxidant α1-Microglobulin (A1M), Including Kidney Damage Assessment Using 99mTc-MAG3 Imaging
Amanda Kristiansson, Anders Örbom, Jonas Ahlstedt, Helena Karlsson, Wahed Zedan, Magnus Gram, Bo Åkerström, Sven-Erik Strand, Mohamed Altai, Joanna Strand, Oskar Vilhelmsson Timmermand
Biomolecules. 2021 Feb; 11(2): 263. Published online 2021 Feb 10. doi: 10.3390/biom11020263
PMCID:
PMC7916794
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Convolutional Neural Network-Based Artificial Intelligence for Classification of Protein Localization Patterns
Kaisa Liimatainen, Riku Huttunen, Leena Latonen, Pekka Ruusuvuori
Biomolecules. 2021 Feb; 11(2): 264. Published online 2021 Feb 11. doi: 10.3390/biom11020264
PMCID:
PMC7916854
Article PubReader PDF–6.5MCite
The Influence of Coumestrol on Sphingolipid Signaling Pathway and Insulin Resistance Development in Primary Rat Hepatocytes
Hubert Zywno, Wiktor Bzdega, Adrian Kolakowski, Piotr Kurzyna, Ewa Harasim-Symbor, Klaudia Sztolsztener, Adrian Chabowski, Karolina Konstantynowicz-Nowicka
Biomolecules. 2021 Feb; 11(2): 268. Published online 2021 Feb 12. doi: 10.3390/biom11020268
PMCID:
PMC7918648
Article PubReader PDF–2.3MCite
Discovery and Characterization of an ALFA-Tag-Specific Affinity Resin Optimized for Protein Purification at Low Temperatures in Physiological Buffer
Markus Kilisch, Hansjörg Götzke, Maja Gere-Becker, Alexander Crauel, Felipe Opazo, Steffen Frey
Biomolecules. 2021 Feb; 11(2): 269. Published online 2021 Feb 12. doi: 10.3390/biom11020269
PMCID:
PMC7918568
Article PubReader PDF–2.3MCite
Quantitative Assessment of 3D Printed Model Accuracy in Delineating Congenital Heart Disease
Shenyuan Lee, Andrew Squelch, Zhonghua Sun
Biomolecules. 2021 Feb; 11(2): 270. Published online 2021 Feb 12. doi: 10.3390/biom11020270
PMCID:
PMC7917618
Article PubReader PDF–2.9MCite
Chemical and Bioinformatics Analyses of the Anti-Leishmanial and Anti-Oxidant Activities of Hemp Essential Oil
Luigi Menghini, Claudio Ferrante, Simone Carradori, Marianna D’Antonio, Giustino Orlando, Francesco Cairone, Stefania Cesa, Antonello Filippi, Caterina Fraschetti, Gokhan Zengin, Gunes Ak, Massimo Tacchini, Kashif Iqbal
Biomolecules. 2021 Feb; 11(2): 272. Published online 2021 Feb 12. doi: 10.3390/biom11020272
PMCID:
PMC7917915
Article PubReader PDF–4.6MCite
Low Expression of miR-375 and miR-190b Differentiates Grade 3 Patients with Endometrial Cancer
Miłosz Pietrus, Michał Seweryn, Przemysław Kapusta, Paweł Wołkow, Kazimierz Pityński, Gracjan Wątor
Biomolecules. 2021 Feb; 11(2): 274. Published online 2021 Feb 13. doi: 10.3390/biom11020274
PMCID:
PMC7918779
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α-Ketoheterocycles Able to Inhibit the Generation of Prostaglandin E2 (PGE2) in Rat Mesangial Cells
Anastasia Psarra, Maria A. Theodoropoulou, Martin Erhardt, Marina Mertiri, Christiana Mantzourani, Sofia Vasilakaki, Victoria Magrioti, Andrea Huwiler, George Kokotos
Biomolecules. 2021 Feb; 11(2): 275. Published online 2021 Feb 13. doi: 10.3390/biom11020275
PMCID:
PMC7918003
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Protective Role of Sphingomyelin in Eye Lens Cell Membrane Model against Oxidative Stress
Mehdi Ravandeh, Giulia Coliva, Heike Kahlert, Amir Azinfar, Christiane A. Helm, Maria Fedorova, Kristian Wende
Biomolecules. 2021 Feb; 11(2): 276. Published online 2021 Feb 13. doi: 10.3390/biom11020276
PMCID:
PMC7918908
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Pharmacological Manipulation of Early Zebrafish Skeletal Development Shows an Important Role for Smad9 in Control of Skeletal Progenitor Populations
Georgina L. K. McDonald, Mengdi Wang, Chrissy L. Hammond, Dylan J. M. Bergen
Biomolecules. 2021 Feb; 11(2): 277. Published online 2021 Feb 13. doi: 10.3390/biom11020277
PMCID:
PMC7918065
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Valency and Binding Affinity Variations Can Regulate the Multilayered Organization of Protein Condensates with Many Components
Ignacio Sanchez-Burgos, Jorge R. Espinosa, Jerelle A. Joseph, Rosana Collepardo-Guevara
Biomolecules. 2021 Feb; 11(2): 278. Published online 2021 Feb 14. doi: 10.3390/biom11020278
PMCID:
PMC7918469
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Methyl Caffeate Isolated from the Flowers of Prunus persica (L.) Batsch Enhances Glucose-Stimulated Insulin Secretion
Dahae Lee, Yutong Qi, Ranhee Kim, Jungbin Song, Hocheol Kim, Hyun Young Kim, Dae Sik Jang, Ki Sung Kang
Biomolecules. 2021 Feb; 11(2): 279. Published online 2021 Feb 14. doi: 10.3390/biom11020279
PMCID:
PMC7917615
Article PubReader PDF–1.9MCite
Serum Acylcarnitines Associated with High Short-Term Mortality in Patients with Alcoholic Hepatitis
Bei Gao, Josepmaria Argemi, Ramon Bataller, Bernd Schnabl
Biomolecules. 2021 Feb; 11(2): 281. Published online 2021 Feb 14. doi: 10.3390/biom11020281
PMCID:
PMC7917657
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Optimization of Exopolysaccharides Production by Porphyridium sordidum and Their Potential to Induce Defense Responses in Arabidopsis thaliana against Fusarium oxysporum
Marwa Drira, Jihen Elleuch, Hajer Ben Hlima, Faiez Hentati, Christine Gardarin, Christophe Rihouey, Didier Le Cerf, Philippe Michaud, Slim Abdelkafi, Imen Fendri
Biomolecules. 2021 Feb; 11(2): 282. Published online 2021 Feb 14. doi: 10.3390/biom11020282
PMCID:
PMC7918794
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Involvement of Cellular Prion Protein in Invasion and Metastasis of Lung Cancer by Inducing Treg Cell Development
Seunghwa Cha, Mi-Ji Sin, Mo-Jong Kim, Hee-Jun Kim, Yong-Sun Kim, Eun-Kyoung Choi, Mi-Yeon Kim
Biomolecules. 2021 Feb; 11(2): 285. Published online 2021 Feb 15. doi: 10.3390/biom11020285
PMCID:
PMC7918983
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Glucagon Prevents Cytotoxicity Induced by Methylglyoxal in a Rat Neuronal Cell Line Model
Mohammad Sarif Mohiuddin, Tatsuhito Himeno, Yuichiro Yamada, Yoshiaki Morishita, Masaki Kondo, Shin Tsunekawa, Yoshiro Kato, Jiro Nakamura, Hideki Kamiya
Biomolecules. 2021 Feb; 11(2): 287. Published online 2021 Feb 15. doi: 10.3390/biom11020287
PMCID:
PMC7919475
Article PubReader PDF–9.2MCite
A Targeted and Tuneable DNA Damage Tool Using CRISPR/Cas9
Ioannis Emmanouilidis, Natalia Fili, Alexander W. Cook, Yukti Hari-Gupta, Ália dos Santos, Lin Wang, Marisa L. Martin-Fernandez, Peter J. I. Ellis, Christopher P. Toseland
Biomolecules. 2021 Feb; 11(2): 288. Published online 2021 Feb 15. doi: 10.3390/biom11020288
PMCID:
PMC7919286
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Determination of Genotoxicity Attributed to Diesel Exhaust Particles in Normal Human Embryonic Lung Cell (WI-38) Line
Joong Won Lee, Hee Jae Lee, Young-Joo Lee, Yong-beom Lim, Woo Jong Sim, Ji-Hye Jang, Hye-Ryeon Heo, Hyun Joung Lim, Ji-Won Jung, Jin Sik Kim
Biomolecules. 2021 Feb; 11(2): 291. Published online 2021 Feb 16. doi: 10.3390/biom11020291
PMCID:
PMC7919825
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Cardiovascular “Patterns” of H2S and SSNO−-Mix Evaluated from 35 Rat Hemodynamic Parameters
Lenka Tomasova, Marian Grman, Anton Misak, Lucia Kurakova, Elena Ondriasova, Karol Ondrias
Biomolecules. 2021 Feb; 11(2): 293. Published online 2021 Feb 16. doi: 10.3390/biom11020293
PMCID:
PMC7920056
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Psychosocial Crowding Stress-Induced Changes in Synaptic Transmission and Glutamate Receptor Expression in the Rat Frontal Cortex
Agnieszka Zelek-Molik, Bartosz Bobula, Anna Gądek-Michalska, Katarzyna Chorązka, Adam Bielawski, Justyna Kuśmierczyk, Marcin Siwiec, Michał Wilczkowski, Grzegorz Hess, Irena Nalepa
Biomolecules. 2021 Feb; 11(2): 294. Published online 2021 Feb 16. doi: 10.3390/biom11020294
PMCID:
PMC7920072
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Fungal Metabolites with Antagonistic Activity against Fungi of Lithic Substrata
Marco Masi, Mariagioia Petraretti, Antonino De Natale, Antonino Pollio, Antonio Evidente
Biomolecules. 2021 Feb; 11(2): 295. Published online 2021 Feb 16. doi: 10.3390/biom11020295
PMCID:
PMC7920264
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Multivalent Display of SARS-CoV-2 Spike (RBD Domain) of COVID-19 to Nanomaterial, Protein Ferritin Nanocages
Umesh Kalathiya, Monikaben Padariya, Robin Fahraeus, Soumyananda Chakraborti, Ted R. Hupp
Biomolecules. 2021 Feb; 11(2): 297. Published online 2021 Feb 17. doi: 10.3390/biom11020297
PMCID:
PMC7923090
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Serum Long Non-Coding RNAs PVT1, HOTAIR, and NEAT1 as Potential Biomarkers in Egyptian Women with Breast Cancer
Amal Ahmed Abd El-Fattah, Nermin Abdel Hamid Sadik, Olfat Gamil Shaker, Amal Mohamed Kamal, Nancy Nabil Shahin
Biomolecules. 2021 Feb; 11(2): 301. Published online 2021 Feb 18. doi: 10.3390/biom11020301
PMCID:
PMC7922136
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New Insights into the Antimicrobial Action of Cinnamaldehyde towards Escherichia coli and Its Effects on Intestinal Colonization of Mice
Wellison A. Pereira, Carlos Drielson S. Pereira, Raíssa G. Assunção, Iandeyara Savanna C. da Silva, Fabrícia S. Rego, Leylane S. R. Alves, Juliana S. Santos, Francisco Jonathas R. Nogueira, Adrielle Zagmignan, Thomas T. Thomsen, Anders Løbner-Olesen, Karen A. Krogfelt, Luís Cláudio N. da Silva, Afonso G. Abreu
Biomolecules. 2021 Feb; 11(2): 302. Published online 2021 Feb 18. doi: 10.3390/biom11020302
PMCID:
PMC7922552
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A Pilot Study for Metabolic Profiling of Obesity-Associated Microbial Gut Dysbiosis in Male Wistar Rats
Julia Hernandez-Baixauli, Pere Puigbò, Helena Torrell, Hector Palacios-Jordan, Vicent J. Ribas Ripoll, Antoni Caimari, Josep M Del Bas, Laura Baselga-Escudero, Miquel Mulero
Biomolecules. 2021 Feb; 11(2): 303. Published online 2021 Feb 18. doi: 10.3390/biom11020303
PMCID:
PMC7922951
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Nitric Oxide Enhances Photosynthetic Nitrogen and Sulfur-Use Efficiency and Activity of Ascorbate-Glutathione Cycle to Reduce High Temperature Stress-Induced Oxidative Stress in Rice (Oryza sativa L.) Plants
Harsha Gautam, Zebus Sehar, Md Tabish Rehman, Afzal Hussain, Mohamed F. AlAjmi, Nafees A. Khan
Biomolecules. 2021 Feb; 11(2): 305. Published online 2021 Feb 18. doi: 10.3390/biom11020305
PMCID:
PMC7922496
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Imaging-Based Staging of Hepatic Fibrosis in Patients with Hepatitis B: A Dynamic Radiomics Model Based on Gd-EOB-DTPA-Enhanced MRI
Rencheng Zheng, Chunzi Shi, Chengyan Wang, Nannan Shi, Tian Qiu, Weibo Chen, Yuxin Shi, He Wang
Biomolecules. 2021 Feb; 11(2): 307. Published online 2021 Feb 18. doi: 10.3390/biom11020307
PMCID:
PMC7922315
Article PubReader PDF–4.2MCite
Comparison of SYK Signaling Networks Reveals the Potential Molecular Determinants of Its Tumor-Promoting and Suppressing Functions
Marion Buffard, Aurélien Naldi, Gilles Freiss, Marcel Deckert, Ovidiu Radulescu, Peter J. Coopman, Romain M. Larive
Biomolecules. 2021 Feb; 11(2): 308. Published online 2021 Feb 18. doi: 10.3390/biom11020308
PMCID:
PMC7923165
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Substrate-Dependent Sensitivity of SIRT1 to Nicotinamide Inhibition
Stacia Rymarchyk, Wenjia Kang, Yana Cen
Biomolecules. 2021 Feb; 11(2): 312. Published online 2021 Feb 18. doi: 10.3390/biom11020312
PMCID:
PMC7922766
Article PubReader PDF–15MCite
Severe Genotype, Pancreatic Insufficiency and Low Dose of Pancreatic Enzymes Associate with Abnormal Serum Sterol Profile in Cystic Fibrosis
Sławomira Drzymała-Czyż, Patrycja Krzyżanowska-Jankowska, Krzysztof Dziedzic, Aleksandra Lisowska, Szymon Kurek, Joanna Goździk-Spychalska, Victoria Kononets, Dagmara Woźniak, Edyta Mądry, Jarosław Walkowiak
Biomolecules. 2021 Feb; 11(2): 313. Published online 2021 Feb 19. doi: 10.3390/biom11020313
PMCID:
PMC7922133
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Enzymatic Synthesis of Lipophilic Esters of Phenolic Compounds, Evaluation of Their Antioxidant Activity and Effect on the Oxidative Stability of Selected Oils
Bartłomiej Zieniuk, Katarzyna Groborz, Małgorzata Wołoszynowska, Katarzyna Ratusz, Ewa Białecka-Florjańczyk, Agata Fabiszewska
Biomolecules. 2021 Feb; 11(2): 314. Published online 2021 Feb 19. doi: 10.3390/biom11020314
PMCID:
PMC7922254
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Skeletal Muscle Transcriptome Analysis of Hanzhong Ma Duck at Different Growth Stages Using RNA-Seq
Zhigang Hu, Junting Cao, Jianqin Zhang, Liyan Ge, Huilin Zhang, Xiaolin Liu
Biomolecules. 2021 Feb; 11(2): 315. Published online 2021 Feb 19. doi: 10.3390/biom11020315
PMCID:
PMC7927120
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Silver Nanoparticles Induce Neutrophil Extracellular Traps Via Activation of PAD and Neutrophil Elastase
HanGoo Kang, Jinwon Seo, Eun-Jeong Yang, In-Hong Choi
Biomolecules. 2021 Feb; 11(2): 317. Published online 2021 Feb 19. doi: 10.3390/biom11020317
PMCID:
PMC7922014
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Looking for Hidden Enemies of Metabarcoding: Species Composition, Habitat and Management Can Strongly Influence DNA Extraction while Examining Grassland Communities
Anna Rucińska, Marcin Olszak, Sebastian Świerszcz, Marcin Nobis, Szymon Zubek, Grzegorz Kusza, Maja Boczkowska, Arkadiusz Nowak
Biomolecules. 2021 Feb; 11(2): 318. Published online 2021 Feb 19. doi: 10.3390/biom11020318
PMCID:
PMC7921978
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Behavioral Effects of Developmental Exposure to JWH-018 in Wild-Type and Disrupted in Schizophrenia 1 (disc1) Mutant Zebrafish
Judit García-González, Bruno de Quadros, William Havelange, Alistair J. Brock, Caroline H. Brennan
Biomolecules. 2021 Feb; 11(2): 319. Published online 2021 Feb 19. doi: 10.3390/biom11020319
PMCID:
PMC7922669
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Pro-Inflammatory Cytokines Induce Insulin and Glucagon Double Positive Human Islet Cells That Are Resistant to Apoptosis
Marta Tesi, Marco Bugliani, Gianmarco Ferri, Mara Suleiman, Carmela De Luca, Emanuele Bosi, Matilde Masini, Vincenzo De Tata, Conny Gysemans, Francesco Cardarelli, Miriam Cnop, Decio L. Eizirik, Piero Marchetti, Lorella Marselli
Biomolecules. 2021 Feb; 11(2): 320. Published online 2021 Feb 19. doi: 10.3390/biom11020320
PMCID:
PMC7923272
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Thermosonication for the Production of Sulforaphane Rich Broccoli Ingredients
Sajad Shokri, Hema Jegasothy, Mary Ann Augustin, Netsanet Shiferaw Terefe
Biomolecules. 2021 Feb; 11(2): 321. Published online 2021 Feb 20. doi: 10.3390/biom11020321
PMCID:
PMC7923798
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Associations of Circulating Irisin with FNDC5 Expression in Fat and Muscle in Type 1 and Type 2 Diabetic Mice
Songling Jiang, Lingjuan Piao, Eun Bi Ma, Hunjoo Ha, Joo Young Huh
Biomolecules. 2021 Feb; 11(2): 322. Published online 2021 Feb 20. doi: 10.3390/biom11020322
PMCID:
PMC7924053
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Adipocytokines in Untreated Newly Diagnosed Rheumatoid Arthritis: Association with Circulating Chemokines and Markers of Inflammation
Georgios K. Vasileiadis, Anna-Carin Lundell, Yuan Zhang, Kerstin Andersson, Inger Gjertsson, Anna Rudin, Cristina Maglio
Biomolecules. 2021 Feb; 11(2): 325. Published online 2021 Feb 21. doi: 10.3390/biom11020325
PMCID:
PMC7924659
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Obesity-Related Changes in Human Plasma Lipidome Determined by the Lipidyzer Platform
Péter Pikó, László Pál, Sándor Szűcs, Zsigmond Kósa, János Sándor, Róza Ádány
Biomolecules. 2021 Feb; 11(2): 326. Published online 2021 Feb 21. doi: 10.3390/biom11020326
PMCID:
PMC7924880
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Dehydration-Induced WRKY Transcriptional Factor MfWRKY70 of Myrothamnus flabellifolia Enhanced Drought and Salinity Tolerance in Arabidopsis
Xiang-Ying Xiang, Jia Chen, Wen-Xin Xu, Jia-Rui Qiu, Li Song, Jia-Tong Wang, Rong Tang, Duoer Chen, Cai-Zhong Jiang, Zhuo Huang
Biomolecules. 2021 Feb; 11(2): 327. Published online 2021 Feb 22. doi: 10.3390/biom11020327
PMCID:
PMC7926768
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Protective Effect of Osmundacetone against Neurological Cell Death Caused by Oxidative Glutamate Toxicity
Tuy An Trinh, Young Hye Seo, Sungyoul Choi, Jun Lee, Ki Sung Kang
Biomolecules. 2021 Feb; 11(2): 328. Published online 2021 Feb 22. doi: 10.3390/biom11020328
PMCID:
PMC7926874
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Structure-Based Virtual Screening of Tumor Necrosis Factor-α Inhibitors by Cheminformatics Approaches and Bio-Molecular Simulation
Sobia Ahsan Halim, Almas Gul Sikandari, Ajmal Khan, Abdul Wadood, Muhammad Qaiser Fatmi, René Csuk, Ahmed Al-Harrasi
Biomolecules. 2021 Feb; 11(2): 329. Published online 2021 Feb 22. doi: 10.3390/biom11020329
PMCID:
PMC7926523
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Screening and Molecular Modeling Evaluation of Food Peptides to Inhibit Key Targets of COVID-19 Virus
Ai-Min Shi, Rui Guo, Qiang Wang, Jin-Rong Zhou
Biomolecules. 2021 Feb; 11(2): 330. Published online 2021 Feb 22. doi: 10.3390/biom11020330
PMCID:
PMC7926797
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Properties of the Extracellular Polymeric Substance Layer from Minimally Grown Planktonic Cells of Listeria monocytogenes
Ogueri Nwaiwu, Lawrence Wong, Mita Lad, Timothy Foster, William MacNaughtan, Catherine Rees
Biomolecules. 2021 Feb; 11(2): 331. Published online 2021 Feb 22. doi: 10.3390/biom11020331
PMCID:
PMC7926710
Article PubReader PDF–2.0MCite
Systemic Photoprotection in Skin Cancer Prevention: Knowledge among Dermatologists
Luca Fania, Francesca Sampogna, Francesco Ricci, Mariafrancesca Hyeraci, Andrea Paradisi, Enzo Palese, Giovanni Di Lella, Sabatino Pallotta, Annarita Panebianco, Eleonora Candi, Elena Dellambra, Damiano Abeni
Biomolecules. 2021 Feb; 11(2): 332. Published online 2021 Feb 23. doi: 10.3390/biom11020332
PMCID:
PMC7926776
Article PubReader PDF–586KCite
Anti-TNF Alpha Antibody Humira with pH-dependent Binding Characteristics: A constant-pH Molecular Dynamics, Gaussian Accelerated Molecular Dynamics, and In Vitro Study
Shih-Ting Hong, Yu-Cheng Su, Yu-Jen Wang, Tian-Lu Cheng, Yeng-Tseng Wang
Biomolecules. 2021 Feb; 11(2): 334. Published online 2021 Feb 23. doi: 10.3390/biom11020334
PMCID:
PMC7926962
Article PubReader PDF–3.0MCite
FITC-Dextran Release from Cell-Embedded Fibrin Hydrogels
Viki Raz Lepsky, Sari Natan, Oren Tchaicheeyan, Avraham Kolel, Merav Zussman, Meital Zilberman, Ayelet Lesman
Biomolecules. 2021 Feb; 11(2): 337. Published online 2021 Feb 23. doi: 10.3390/biom11020337
PMCID:
PMC7926394
Article PubReader PDF–3.1MCite
Fungal X-Intrinsic Protein Aquaporin from Trichoderma atroviride: Structural and Functional Considerations
Maroua Ben Amira, Mohamed Faize, Magnus Karlsson, Mukesh Dubey, Magdalena Frąc, Jacek Panek, Boris Fumanal, Aurélie Gousset-Dupont, Jean-Louis Julien, Hatem Chaar, Daniel Auguin, Robin Mom, Philippe Label, Jean-Stéphane Venisse
Biomolecules. 2021 Feb; 11(2): 338. Published online 2021 Feb 23. doi: 10.3390/biom11020338
PMCID:
PMC7927018
Article PubReader PDF–35MCite

Editorials

Enzymatic Inhibitors from Natural Sources: A Huge Collection of New Potential Drugs
Paolo Paoli
Biomolecules. 2021 Feb; 11(2): 133. Published online 2021 Jan 20. doi: 10.3390/biom11020133
PMCID:
PMC7909571
Article PubReader PDF–189KCite
Recent Advances of Actinomycetes
Eung-Soo Kim
Biomolecules. 2021 Feb; 11(2): 134. Published online 2021 Jan 21. doi: 10.3390/biom11020134
PMCID:
PMC7909820
Article PubReader PDF–172KCite
Acknowledgment to Reviewers of Biomolecules in 2020
Biomolecules Editorial Office
Biomolecules. 2021 Feb; 11(2): 151. Published online 2021 Jan 25. doi: 10.3390/biom11020151
PMCID:
PMC7910961
Article PubReader PDF–364KCite
Connexins, Innexins, and Pannexins: From Biology to Clinical Targets
Trond Aasen
Biomolecules. 2021 Feb; 11(2): 155. Published online 2021 Jan 25. doi: 10.3390/biom11020155
PMCID:
PMC7912696
Article PubReader PDF–216KCite
Cell-Free Approaches and Therapeutic Biomolecules for Cardiac Regeneration
Mariann Gyöngyösi
Biomolecules. 2021 Feb; 11(2): 161. Published online 2021 Jan 26. doi: 10.3390/biom11020161
PMCID:
PMC7911580
Article PubReader PDF–156KCite
Special Issue “Role of NRF2 in Disease: Novel Molecular Mechanisms and Therapeutic Approaches”
Isabel Lastres-Becker
Biomolecules. 2021 Feb; 11(2): 202. Published online 2021 Feb 2. doi: 10.3390/biom11020202
PMCID:
PMC7912791
Article PubReader PDF–173KCite
Recent Advances in p53
Gabriella D’Orazi
Biomolecules. 2021 Feb; 11(2): 211. Published online 2021 Feb 3. doi: 10.3390/biom11020211
PMCID:
PMC7913554
Article PubReader PDF–171KCite
The Amazing World of IDPs in Human Diseases
Simona Maria Monti, Giuseppina De Simone, Emma Langella
Biomolecules. 2021 Feb; 11(2): 333. Published online 2021 Feb 23. doi: 10.3390/biom11020333
PMCID:
PMC7926885
Article PubReader PDF–184KCite
Recent Advances in Cancer Immunotherapy
Kenichi Suda
Biomolecules. 2021 Feb; 11(2): 335. Published online 2021 Feb 23. doi: 10.3390/biom11020335
PMCID:
PMC7927083
Article PubReader PDF–148KCite

Communications

Small-Molecule Anti-HIV-1 Agents Based on HIV-1 Capsid Proteins
Takuya Kobayakawa, Masaru Yokoyama, Kohei Tsuji, Masayuki Fujino, Masaki Kurakami, Sayaka Boku, Miyuki Nakayama, Moemi Kaneko, Nami Ohashi, Osamu Kotani, Tsutomu Murakami, Hironori Sato, Hirokazu Tamamura
Biomolecules. 2021 Feb; 11(2): 208. Published online 2021 Feb 3. doi: 10.3390/biom11020208
PMCID:
PMC7913237
Article PubReader PDF–9.0MCite
In Silico Screening of Natural Products Isolated from Mexican Herbal Medicines against COVID-19
Nadia A. Rivero-Segura, Juan C. Gomez-Verjan
Biomolecules. 2021 Feb; 11(2): 216. Published online 2021 Feb 4. doi: 10.3390/biom11020216
PMCID:
PMC7913859
Article PubReader PDF–2.7MCite
Green Biosynthesis of Silver Nanoparticles Using Leaf Extract of Carissa carandas L. and Their Antioxidant and Antimicrobial Activity against Human Pathogenic Bacteria
Reetika Singh, Christophe Hano, Gopal Nath, Bechan Sharma
Biomolecules. 2021 Feb; 11(2): 299. Published online 2021 Feb 17. doi: 10.3390/biom11020299
PMCID:
PMC7922588
Article PubReader PDF–2.0MCite

Perspective

Therapeutic Potential of αS Evolvability for Neuropathic Gaucher Disease
Jianshe Wei, Yoshiki Takamatsu, Ryoko Wada, Masayo Fujita, Gilbert Ho, Eliezer Masliah, Makoto Hashimoto
Biomolecules. 2021 Feb; 11(2): 289. Published online 2021 Feb 15. doi: 10.3390/biom11020289
PMCID:
PMC7919466
Article PubReader PDF–1.4MCite
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