1948-7193 - PMC

Carla Hassler, Yanan Zhang, Brian Gilmour, Tyler Graf, Timothy Fennell, Rodney Snyder, Jeffrey R. Deschamps, Rainer K. Reinscheid, Celia Garau, Scott P. Runyon

ACS Chem Neurosci. 2014 Aug 20; 5(8): 731–744. Published online 2014 Jun 25. doi: 10.1021/cn500113c

PMCID:: PMC4140596

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Multifunctional D2/D3 Agonist D-520 with High in Vivo Efficacy: Modulator of Toxicity of Alpha-Synuclein Aggregates

Gyan Modi, Chandrashekhar Voshavar, Sanjib Gogoi, Mrudang Shah, Tamara Antonio, Maarten E. A. Reith, Aloke K. Dutta

ACS Chem Neurosci. 2014 Aug 20; 5(8): 700–717. Published online 2014 Jun 24. doi: 10.1021/cn500084x

PMCID:: PMC4140597

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Current Hypotheses of Lithium’s Mechanism of Action as a Neuropsychiatric Medication

Galila Agam

ACS Chem Neurosci. 2014 Jun 18; 5(6): 410. Published online 2014 Jun 18. doi: 10.1021/cn5001183

PMCID:: PMC4063505

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Optimization of 6-Heterocyclic-2-(1H-pyrazol-1-yl)-N-(pyridin-2-yl)pyrimidin-4-amine as Potent Adenosine A_2A Receptor Antagonists for the Treatment of Parkinson’s Disease

Jiyue Zheng, Zhaohui Yang, Xuan Li, Linlang Li, Haikuo Ma, Meiyu Wang, Hongjian Zhang, Xuechu Zhen, Xiaohu Zhang

ACS Chem Neurosci. 2014 Aug 20; 5(8): 674–682. Published online 2014 Jun 12. doi: 10.1021/cn5000716

PMCID:: PMC4140592

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Harnessing Mechanobiology of Human Pluripotent Stem Cells for Regenerative Medicine

Yubing Sun, Jianping Fu

ACS Chem Neurosci. 2014 Aug 20; 5(8): 621–623. Published online 2014 Jun 5. doi: 10.1021/cn5001155

PMCID:: PMC4140584

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Histamine H₃ Receptor Activation Counteracts Adenosine A_2A Receptor-Mediated Enhancement of Depolarization-Evoked [³H]-GABA Release from Rat Globus Pallidus Synaptosomes

Guadalupe-Elide Morales-Figueroa, Ricardo Márquez-Gómez, Raúl González-Pantoja, Juan Escamilla-Sánchez, José-Antonio Arias-Montaño

ACS Chem Neurosci. 2014 Aug 20; 5(8): 637–645. Published online 2014 Jun 2. doi: 10.1021/cn500001m

PMCID:: PMC4140591

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Lithium, Inositol and Mitochondria

Lilach Toker, Galila Agam

ACS Chem Neurosci. 2014 Jun 18; 5(6): 411–412. Published online 2014 Jun 2. doi: 10.1021/cn5001149

PMCID:: PMC4063499

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Development of a New Photochromic Ion Channel Blocker via Azologization of Fomocaine

Matthias Schoenberger, Arunas Damijonaitis, Zinan Zhang, Daniel Nagel, Dirk Trauner

ACS Chem Neurosci. 2014 Jul 16; 5(7): 514–518. Published online 2014 May 23. doi: 10.1021/cn500070w

PMCID:: PMC4102962

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Astrocytes and Huntington’s Disease

Baljit S. Khakh, Michael V. Sofroniew

ACS Chem Neurosci. 2014 Jul 16; 5(7): 494–496. Published online 2014 May 20. doi: 10.1021/cn500100r

PMCID:: PMC4102957

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Synthesis of a FTO Inhibitor with Anticonvulsant Activity

Guanqun Zheng, Thomas Cox, Leah Tribbey, Gloria Z. Wang, Paulina Iacoban, Matthew E. Booher, Gregory J. Gabriel, Lu Zhou, Nancy Bae, Joie Rowles, Chuan He, Mark J. Olsen

ACS Chem Neurosci. 2014 Aug 20; 5(8): 658–665. Published online 2014 May 18. doi: 10.1021/cn500042t

PMCID:: PMC4140589

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A Novel Class of Succinimide-Derived Negative Allosteric Modulators of Metabotropic Glutamate Receptor Subtype 1 Provides Insight into a Disconnect in Activity between the Rat and Human Receptors

Hyekyung P. Cho, Darren W. Engers, Daryl F. Venable, Colleen M. Niswender, Craig W. Lindsley, P. Jeffrey Conn, Kyle A. Emmitte, Alice L. Rodriguez

ACS Chem Neurosci. 2014 Jul 16; 5(7): 597–610. Published online 2014 May 5. doi: 10.1021/cn5000343

PMCID:: PMC4102972

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Synthesis, Pharmacological Characterization, and Structure–Activity Relationship Studies of Small Molecular Agonists for the Orphan GPR88 Receptor

Chunyang Jin, Ann M. Decker, Xi-Ping Huang, Brian P. Gilmour, Bruce E. Blough, Bryan L. Roth, Yang Hu, Joseph B. Gill, X. Peter Zhang

ACS Chem Neurosci. 2014 Jul 16; 5(7): 576–587. Published online 2014 May 2. doi: 10.1021/cn500082p

PMCID:: PMC4102971

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Eye Movements as a Probe of Corollary Discharge Function in Schizophrenia

Christopher C. Pack

ACS Chem Neurosci. 2014 May 21; 5(5): 326–328. Published online 2014 May 1. doi: 10.1021/cn5000869

PMCID:: PMC4030793

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Image-Guided Synthesis Reveals Potent Blood-Brain Barrier Permeable Histone Deacetylase Inhibitors

Young Jun Seo, Yeona Kang, Lisa Muench, Alicia Reid, Shannon Caesar, Logan Jean, Florence Wagner, Edward Holson, Stephen J. Haggarty, Philipp Weiss, Payton King, Pauline Carter, Nora D. Volkow, Joanna S. Fowler, Jacob M. Hooker, Sung Won Kim

ACS Chem Neurosci. 2014 Jul 16; 5(7): 588–596. Published online 2014 Apr 29. doi: 10.1021/cn500021p